CAS 1367369-77-4

Entecavir EP Impurity B HCl

CAS: 1367369-77-4

Formula: C₁₂H₁₅N₅O₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 277.29 36.46

Ref: 4Z-E-239

3’-epi-Entecavir

Controlled Product

CAS: 1367369-77-4

Impurity Entecavir EP Impurity B
Applications An epimeric impurity of the antiviral drug Entecavir (E558900).

Formula: C₁₂H₁₅N₅O₃

Color and Shape: Neat

Molecular weight: 277.279

Ref: TR-E558925

Entecavir (1S,3S,4S) diastereomer

CAS: 1367369-77-4

Entecavir is a drug product that is custom synthesized to order. It has a purity of >98% and is made up of the 1S,3S,4S diastereomer. Entecavir is an antiviral drug that belongs to the nucleoside analog family and inhibits viral replication by inhibiting DNA polymerase α. The metabolism studies for entecavir have been completed and it was found that entecavir undergoes hydrolysis by esterases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Entecavir also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Formula: C₁₂H₁₅N₅O₃

Purity: Min. 95%

Molecular weight: 277.28 g/mol

Ref: 3D-IE145299

Entecavir EP Impurity B

CAS: 1367369-77-4

Formula: C₁₂H₁₅N₅O₃

Molecular weight: 277.28

Ref: ST-EA-CP-E36002