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CAS 136765-35-0

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HALOPERIDOL-D4

Description:
Haloperidol-D4 is a deuterated form of haloperidol, an antipsychotic medication primarily used to treat schizophrenia and acute psychosis. The "D4" designation indicates that four hydrogen atoms in the haloperidol molecule have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the compound's stability and alter its pharmacokinetic properties, making it useful in research applications, particularly in studies involving drug metabolism and pharmacodynamics. Haloperidol itself functions as a dopamine antagonist, primarily targeting D2 dopamine receptors in the brain, which helps to mitigate symptoms of psychosis. The deuterated version may also be employed in tracer studies to investigate the drug's behavior in biological systems without altering its therapeutic effects significantly. Haloperidol-D4 is typically characterized by its molecular structure, which retains the core features of haloperidol while exhibiting distinct isotopic labeling, allowing for advanced analytical techniques such as mass spectrometry to track its distribution and metabolism in various biological contexts.
Formula:C21H19ClD4FNO2
Synonyms:
  • 4-[4-(4-Chlorophenyl-d4)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone
  • Aloperidin-d4
  • Bioperidolo-d4
  • Brotopon-d4
  • Dozic-d4
  • Einalon S-d
  • R-1625-d4
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