CAS 136794-87-1

NOR-BETA-CIT

Description:

NOR-BETA-CIT, also known by its chemical name, is a compound that belongs to the class of substances known as selective serotonin reuptake inhibitors (SSRIs). It is primarily studied for its potential applications in pharmacology, particularly in the treatment of mood disorders. The compound is characterized by its ability to selectively inhibit the reuptake of serotonin, a neurotransmitter that plays a crucial role in regulating mood, anxiety, and overall emotional well-being. NOR-BETA-CIT has a specific molecular structure that contributes to its pharmacological activity, and it is often evaluated for its efficacy and safety in clinical settings. Additionally, its chemical properties, such as solubility and stability, are important for formulation in pharmaceutical applications. As with many compounds in this category, understanding its mechanism of action, potential side effects, and interactions with other medications is essential for its therapeutic use. Research continues to explore its full range of effects and potential benefits in treating various psychological conditions.

Formula: C₁₅H₁₈INO₂

InChI: InChI=1/C15H18INO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3

SMILES: COC(=O)C1C(CC2CCC1N2)c1ccc(cc1)I

Synonyms:

• Nor-2-Cit
• 8-Azabicyclo[3.2.1]Octane-2-Carboxylic Acid, 3-(4-Iodophenyl), Methyl Ester, (1R, 2S, 3S, 5S)
• (-)-2-Beta-Carbomethoxy-3-Beta-(4-Iodophenyl) Nortropane
• (-)-2-Beta-Carbomethoxy-3-Beta-(Iodophenyl)Nortropane
• Nor-B-Cit \ Analog Of Dopamine Transport
• (-)-2b-Carbomethoxy-3b-(4-iodophenyl)nortropane
• nor-b-CIT
• methyl (1R)-3-(4-iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
• Methyl 3-(4-Iodophenyl)-8-Azabicyclo[3.2.1]Octane-2-Carboxylate

(-)-2β-Carbomethoxy-3β-(4-iodophenyl)nortropane

CAS: 136794-87-1

Formula: C₁₅H₁₈INO₂

Molecular weight: 371.21

Ref: 7W-GK5800

(-)-2β-Carbomethoxy-3β-(4-iodophenyl)nortropane

Controlled Product

CAS: 136794-87-1

Applications An inhibitor of the serotonin (5-HT) transporter.
References Bergstrom, K.A., et al.: Eur. J. Nucl. Med., 24, 596 (1997), Booij, J., et al.: Eur. J. Nucl. Med., 25, 1666 (1998), Reneman, L., et al.: Synapse, 34, 77 (1999)

Formula: C₁₅H₁₈INO₂

Color and Shape: Neat

Molecular weight: 371.21

Ref: TR-C176610

(-)-2β-Carbomethoxy-3β-(4-iodophenyl)nortropane

Controlled Product

CAS: 136794-87-1

(-)-2b-Carbomethoxy-3b-(4-iodophenyl)nortropane is a serotonin agonist that has been shown to be effective in the treatment of dysthymia and depression in women. It is a serotonergic agent that binds to serotonin receptors, as well as dopamine receptors, which are involved in the regulation of mood. (-)-2b-Carbomethoxy-3b-(4-iodophenyl)nortropane inhibits the reuptake of serotonin, which leads to an increase in the extracellular concentration of serotonin. This agent also has alkylation properties and can form adducts with thiol groups on proteins, such as 5-HT receptors. A positron emission tomography (PET) study found that (-)-2b-Carbomethoxy-3b-(4-iodophenyl)nortropane is a potent radiotracer for mapping the serotonin transporter system

Formula: C₁₅H₁₈INO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 371.21 g/mol

Ref: 3D-FC19718