CAS 136816-75-6
:Atevirdine
Description:
Atevirdine is a synthetic compound classified as a non-nucleoside reverse transcriptase inhibitor (NNRTI), primarily developed for the treatment of HIV infection. It functions by selectively inhibiting the reverse transcriptase enzyme, which is crucial for the replication of the HIV virus. Atevirdine exhibits a unique chemical structure that allows it to bind to the enzyme, thereby preventing the conversion of viral RNA into DNA, a critical step in the viral life cycle. The compound is characterized by its moderate lipophilicity, which influences its absorption and distribution in the body. Atevirdine has been studied for its efficacy and safety profile, although it is not widely used in clinical practice compared to other antiretroviral agents. Its pharmacokinetics, including metabolism and excretion, are important for understanding its therapeutic potential and interactions with other medications. Overall, Atevirdine represents a significant area of research in the ongoing efforts to develop effective treatments for HIV/AIDS.
Formula:C21H25N5O2
InChI:InChI=1S/C21H25N5O2/c1-3-22-18-5-4-8-23-20(18)25-9-11-26(12-10-25)21(27)19-14-15-13-16(28-2)6-7-17(15)24-19/h4-8,13-14,22,24H,3,9-12H2,1-2H3
InChI key:InChIKey=UCPOMLWZWRTIAA-UHFFFAOYSA-N
SMILES:N(CC)C1=C(N=CC=C1)N2CCN(C(=O)C3=CC=4C(N3)=CC=C(OC)C4)CC2
Synonyms:- [4-[3-(Ethylamino)-2-pyridinyl]-1-piperazinyl](5-methoxy-1H-indol-2-yl)methanone
- Methanone, [4-[3-(ethylamino)-2-pyridinyl]-1-piperazinyl](5-methoxy-1H-indol-2-yl)-
- 1-[3-(Ethylamino)-2-pyridyl]-4-[(5-methoxyindol-2-yl)carbonyl]piperazine
- U 87201
- Piperazine, 1-[3-(ethylamino)-2-pyridinyl]-4-[(5-methoxy-1H-indol-2-yl)carbonyl]-
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Found 2 products.
Atevirdine
CAS:<p>Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).</p>Formula:C21H25N5O2Purity:98.20%Color and Shape:SolidMolecular weight:379.46
