CAS 136834-22-5
:2'-Fluoro-N6-Bz-5'-O-DMT-2'-deoxyadenosine-3'-CE-Phosphoramidite
Description:
2'-Fluoro-N6-Bz-5'-O-DMT-2'-deoxyadenosine-3'-CE-Phosphoramidite is a modified nucleoside analog used primarily in the field of oligonucleotide synthesis. This compound features a 2'-fluoro modification, which enhances the stability and binding affinity of the nucleoside, making it particularly useful in the development of antisense oligonucleotides and other therapeutic applications. The N6-benzoyl (Bz) group serves as a protective moiety for the amine group, while the 5'-O-DMT (dimethoxytrityl) group protects the 5' hydroxyl, facilitating the stepwise addition of nucleotides during synthesis. The 3'-CE (cyanoethyl) phosphoramidite functionality allows for the formation of phosphodiester bonds, essential for constructing nucleic acid chains. Overall, this compound is characterized by its enhanced stability, specificity, and utility in nucleic acid research and therapeutic development, making it a valuable tool in molecular biology and genetic engineering.
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Found 10 products.
DMT-2'-Fluoro-dA(Bz) Phosphoramidite
CAS:Formula:C47H51FN7O7PPurity:>90.0%(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:875.94N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxyadenosine-3'-(2-cyanoethyl diisopropylphosphoramidite), 98%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Formula:C47H51FN7O7PPurity:98%Color and Shape:White to off-white, Powder or crystals or crystalline powder or flakesMolecular weight:875.94Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS:Formula:C47H51FN7O7PPurity:95%Color and Shape:SolidMolecular weight:875.9227Ref: IN-DA0012FC
1g84.00€5g182.00€10g314.00€1kgTo inquire25gTo inquire100mg35.00€250mg54.00€500mg68.00€(2R,3R,4R,5R)-5-(6-Benzamido-9H-Purin-9-Yl)-2-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)-4-Fluorotetrahydrofuran-3-Yl (2-Cyanoethyl) Diisopropylphosphoramidite
CAS:<p>(2R,3R,4R,5R)-5-(6-Benzamido-9H-Purin-9-Yl)-2-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)-4-Fluorotetrahydrofuran-3-Yl (2-Cyanoethyl) Diisopropylphosphoramidite</p>Purity:98%Molecular weight:875.92g/molDmt-2'fluoro-da(bz) amidite
CAS:<p>Dmt-2'fluoro-da(bz) amidite</p>Purity:≥98%Molecular weight:875.92g/molDmt-2'fluoro-da(bz) amidite
CAS:<p>DMT-2'Fluoro-DA(Bz) amidite: 2'-deoxy-2'-fluoro oligo with RNA affinity; precursor to antisense 5'-DMT-3'-phosphoramidite.</p>Formula:C47H51FN7O7PPurity:98.15%Color and Shape:SolidMolecular weight:875.92N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite
CAS:<p>Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides. N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite, also known as 2'-fluoro-dA CEP, is a modified adenosine with a fluorine atom in the 2’ position to enable the synthesis of non-natural fluorine containing oligonucleotides. Nucleoside phosphoramidites are typically modified by displacement of the diisopropylamine group with the 5’ hydroxyl of the next nucleoside in the presence of an azole catalyst such as 1H-tetrazole or 4,5-dicyanoimidazole. 2'-Fluoro-dA CEP has been used in the synthesis of phosphorothioate oligonucleotides that were highly nuclease resistant yet retained exceptional binding affinity to the RNA targets.</p>Formula:C47H51FN7O7PPurity:97%Color and Shape:PowderMolecular weight:875.95 g/molRef: 4Z-A-267081
Discontinued product
![Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0012FC.jpg&w=3840&q=75)
