CAS 136834-22-5: 2'-Fluoro-N6-Bz-5'-O-DMT-2'-deoxyadenosine-3'-CE-Phosphoramidite

Description: 2'-Fluoro-N6-Bz-5'-O-DMT-2'-deoxyadenosine-3'-CE-Phosphoramidite is a modified nucleoside analog used primarily in the field of oligonucleotide synthesis. This compound features a 2'-fluoro modification, which enhances the stability and binding affinity of the nucleoside, making it particularly useful in the development of antisense oligonucleotides and other therapeutic applications. The N6-benzoyl (Bz) group serves as a protective moiety for the amine group, while the 5'-O-DMT (dimethoxytrityl) group protects the 5' hydroxyl, facilitating the stepwise addition of nucleotides during synthesis. The 3'-CE (cyanoethyl) phosphoramidite functionality allows for the formation of phosphodiester bonds, essential for constructing nucleic acid chains. Overall, this compound is characterized by its enhanced stability, specificity, and utility in nucleic acid research and therapeutic development, making it a valuable tool in molecular biology and genetic engineering.

DMT-2'-Fluoro-dA(Bz) Phosphoramidite

CAS: 136834-22-5

• Formula: C₄₇H₅₁FN₇O₇P
• Purity: >90.0%(qNMR)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 875.94

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxyadenosine-3'-(2-cyanoethyl diisopropylphosphoramidite), 98%

CAS: 136834-22-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. …

• Formula: C₄₇H₅₁FN₇O₇P
• Purity: 98%
• Color and Shape: White to off-white, Powder or crystals or crystalline powder or flakes
• Molecular weight: 875.94

Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS: 136834-22-5

• Formula: C₄₇H₅₁FN₇O₇P
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 875.9227

(2R,3R,4R,5R)-5-(6-Benzamido-9H-Purin-9-Yl)-2-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)-4-Fluorotetrahydrofuran-3-Yl (2-Cyanoethyl) Diisopropylphosphoramidite

CAS: 136834-22-5

• Purity: 98%
• Molecular weight: 875.92g/mol

Dmt-2'fluoro-da(bz) amidite

CAS: 136834-22-5

• Purity: 98.15%
• Molecular weight: 875.92g/mol

DMT-2'-Fluoro-dA(Bz) phosphoramidite

CAS: 136834-22-5

• Formula: C₄₇H₅₁FN₇O₇P
• Molecular weight: 875.94

Dmt-2'fluoro-da(bz) amidite

CAS: 136834-22-5

DMT-2'Fluoro-DA(Bz) amidite: 2'-deoxy-2'-fluoro oligo with RNA affinity; precursor to antisense 5'-DMT-3'-phosphoramidite.

• Formula: C₄₇H₅₁FN₇O₇P
• Purity: 98.15%
• Color and Shape: Liquid
• Molecular weight: 875.92

N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite

CAS: 136834-22-5

Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides. N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite, also known …

• Formula: C₄₇H₅₁FN₇O₇P
• Purity: 97%
• Color and Shape: Powder
• Molecular weight: 875.95 g/mol