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CAS 136859-76-2

:

8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE

Description:
8-Hydroxy-N2-isobutryl-2'-deoxyguanosine (CAS 136859-76-2) is a modified nucleoside that features a hydroxyl group at the 8-position of the guanine base and an isobutyryl group at the N2 position. This compound is of interest in biochemical and pharmacological research due to its potential role in studying DNA damage and repair mechanisms, particularly oxidative stress. The presence of the hydroxyl group can influence the nucleoside's reactivity and interactions with other biomolecules, potentially affecting its incorporation into DNA and its stability. Additionally, the isobutyryl modification may impact the compound's solubility and biological activity. As a nucleoside analog, it can serve as a valuable tool in understanding the effects of oxidative modifications on nucleic acids and may have implications in cancer research and therapeutic development. Its unique structural features make it a subject of interest for further studies in molecular biology and medicinal chemistry.
Formula:C14H19N5O6
Synonyms:
  • 8-Hydroxy-N2-Isobutyryl-2'-Deoxyguanosine
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