CAS 137-00-8

4-Methyl-5-(2-hydroxyethyl)thiazole

Description:

4-Methyl-5-(2-hydroxyethyl)thiazole, with the CAS number 137-00-8, is an organic compound characterized by its thiazole ring, which is a five-membered heterocyclic structure containing both sulfur and nitrogen. This compound features a methyl group at the 4-position and a hydroxyethyl group at the 5-position of the thiazole ring, contributing to its unique chemical properties. It is typically a colorless to pale yellow liquid or solid, depending on its form and purity. The presence of the hydroxyethyl group enhances its solubility in polar solvents, making it useful in various applications, including as a flavoring agent and in the synthesis of other organic compounds. Additionally, 4-Methyl-5-(2-hydroxyethyl)thiazole may exhibit biological activity, which can be of interest in pharmaceutical research. Its stability and reactivity can be influenced by environmental factors such as pH and temperature, making it important to consider these conditions in practical applications. Overall, this compound is notable for its structural features and potential utility in both industrial and research settings.

Formula: C₆H₉NOS

InChI: InChI=1S/C6H9NOS/c1-5-6(2-3-8)9-4-7-5/h4,8H,2-3H2,1H3

InChI key: InChIKey=BKAWJIRCKVUVED-UHFFFAOYSA-N

SMILES: C(CO)C1=C(C)N=CS1

Synonyms:

• 2-(4-Methyl-1,3-Thiazol-5-Yl)Ethanol
• 2-(4-Methyl-1,3-thiazol-5-yl)ethan-1-ol
• 2-(4-Methyl-5-thiazolyl)-ethanol
• 2-(4-Methylthiazole-5-yl)ethanol
• 4-Methyl-5-(2'-hydroxyethyl)-thiazole
• 4-Methyl-5-(2-thiazoleethanol)
• 4-Methyl-5-(β-hydroxyethyl))thiazole
• 4-Methyl-5-Beta-Hydroxyxyethyl Thiazole
• 4-Methyl-5-Hydroxyethyl-Thiazole
• 4-Methyl-5-beta-hydroxyethyl thiazole
• 4-Methyl-5-thiazolylethanol
• 5-(2-Hydroxyethyl)-3-methylthiazole~Sulfurol
• 5-(2-Hydroxyethyl)-4-methylthiazole
• 5-(Hydroxyethyl)-4-methylthiazole
• 5-(β-Hydroxyethyl)-4-methylthiazole
• 5-Hydroxyethyl-4-methyl thiazole
• 5-Thiazoleethanol, 4-methyl-
• Hemineurine
• NSC 23262
• NSC 41831
• Sulfurol

5-(2-Hydroxyethyl)-4-methylthiazole

CAS: 137-00-8

Formula: C₆H₉NOS

Purity: >98.0%(GC)

Color and Shape: Colorless to Yellow to Green clear liquid

Molecular weight: 143.20

Ref: 3B-H0527

4-Methyl-5-thiazoleethanol, 98%

CAS: 137-00-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₉NOS

Purity: 98%

Color and Shape: Liquid or viscous liquid, Clear colorless to yellow to orange to brown

Molecular weight: 143.20

Ref: 02-A13567

Clomethiazole impurity C

CAS: 137-00-8

Clomethiazole impurity C

Formula: C₆H₉NOS

Color and Shape: Yellow Liquid

Molecular weight: 143.2068

Ref: 47-444

5-Thiazoleethanol, 4-methyl-

CAS: 137-00-8

Formula: C₆H₉NOS

Purity: 98%

Color and Shape: Liquid

Molecular weight: 143.2068

Ref: IN-DA0012ON

Thiamine Impurity 2

CAS: 137-00-8

Formula: C₆H₉NOS

Molecular weight: 143.20

Ref: 4Z-T-8423

4-Methyl-5-thiazoleethanol (5-(2-Hydroxyethyl)-4-methylthiazole)

CAS: 137-00-8

Formula: C₆H₉NOS

Molecular weight: 143.21

Ref: 7W-GK4527

5-(2-Hydroxyethyl)-4-methylthiazole

Controlled Product

CAS: 137-00-8

Formula: C₆H₉NOS

Color and Shape: Yellow To Brown

Molecular weight: 143.21

Ref: 86-MM0049.02

4-Methylthiazol-5ylethanol

CAS: 137-00-8

4-Methylthiazol-5ylethanol

Formula: C₆H₉NOS

Purity: 98%

Color and Shape: light yellow to yellow liquid

Molecular weight: 143.21g/mol

Ref: 54-OR2678

4-Methyl-5-thiazoleethanol-13C3 (~90%)

Controlled Product

CAS: 137-00-8

Applications 4-Methyl-5-thiazoleethanol-13C3 is used in the synthesis of novel HldE kinase inhibitors used against gram negative bacteria. Also used in the synthesis of potential antimalarial agents from bis-thiazolium analogues. Refer to M330235.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Desroy, N. et al.: J. Med. CHem., 56, 1418 (2013); Caldarelli, S. et al.: J. Med. CHem., 496, (2013);

Formula: C₃C₃H₉NOS

Purity: ~90%

Color and Shape: Neat

Molecular weight: 146.185

Ref: TR-M330237

4-Methyl-5-thiazoleethanol

CAS: 137-00-8

Applications 4-Methyl-5-thiazoleethanol is used in the synthesis of novel HldE kinase inhibitors used against gram negative bacteria. Also used in the synthesis of potential antimalarial agents from bis-thiazolium analogues.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Desroy, N. et al.: J. Med. CHem., 56, 1418 (2013); Caldarelli, S. et al.: J. Med. CHem., 496, (2013);

Formula: C₆H₉NOS

Color and Shape: Neat

Molecular weight: 143.21

Ref: TR-M330235

2-(4-Methyl-1,3-thiazol-5-yl)ethanol

CAS: 137-00-8

Formula: C₆H₉NOS

Purity: 95%

Color and Shape: Liquid

Molecular weight: 143.2

Ref: 10-F067726

5-Hydroxyethyl-4-methylthiazole

CAS: 137-00-8

5-Hydroxyethyl-4-methylthiazole (5HET) is a chemical that has been shown to inhibit the growth of some wild-type strains of bacteria. It has been found to bind to the bacterial cell membrane and prevent the transport of nutrients into the cell. This leads to a decrease in ATP synthesis and metabolic disorders. 5HET also inhibits caproic acid oxidation, which may be related to its cytosolic Ca2+ response. 5HET binds with high affinity to DNA and RNA, making it an excellent candidate for use in biochemical experiments involving these biomolecules. The binding site for 5HET is not yet known, but it is hypothesized that this compound interacts with nucleic acids by electrostatic interactions or hydrogen bonding.

Formula: C₆H₉NOS

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 143.21 g/mol

Ref: 3D-FH54860

Thiamine Impurity 39

CAS: 137-00-8

Formula: C₆H₉NOS

Molecular weight: 143.2

Ref: ST-EA-CP-T2063