CAS 137-53-1

Dextrothyroxine sodium

Description:

Dextrothyroxine sodium, with the CAS number 137-53-1, is a synthetic derivative of thyroxine (T4), primarily used in the treatment of obesity and as a thyroid hormone replacement therapy. It is characterized by its ability to stimulate metabolic processes, thereby promoting weight loss and increasing energy expenditure. The compound is a sodium salt, which enhances its solubility in water, facilitating its administration and absorption in the body. Dextrothyroxine sodium exhibits a similar mechanism of action to natural thyroid hormones, influencing various physiological functions, including growth, metabolism, and thermogenesis. It is typically administered in a controlled dosage to avoid potential side effects associated with thyroid hormone excess, such as cardiovascular issues or hyperthyroidism. The substance is also subject to regulatory scrutiny due to its potential for misuse in weight management. Overall, dextrothyroxine sodium is a potent compound with specific therapeutic applications, necessitating careful monitoring during its use.

Formula: C₁₅H₁₁I₄NO₄·Na

InChI: InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/t12-;/m1./s1

InChI key: InChIKey=BRLSOHUOWVCKNI-UTONKHPSSA-N

SMILES: O(C1=CC(I)=C(O)C(I)=C1)C2=C(I)C=C(C[C@H](C(O)=O)N)C=C2I.[Na]

Synonyms:

• <span class="text-smallcaps">D</span>-Thyroxine monosodium salt
• <span class="text-smallcaps">D</span>-Thyroxine sodium
• <span class="text-smallcaps">D</span>-Thyroxine sodium salt
• <span class="text-smallcaps">D</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt
• <span class="text-smallcaps">D</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)
• Biotirmone
• Choloxin
• D-Thyroxine Sodsium Salt
• D-thyroxine, sodium salt
• Debetrol
• Dethyrona
• Detyroxin
• Dextroid
• Dextroxin
• Dynothel
• Eulipos
• Lisolipin
• Nadrothyron D
• Sodium <span class="text-smallcaps">D</span>-3,3′,5,5′-tetraiodothyronine
• Sodium <span class="text-smallcaps">D</span>-thyroxine
• Sodium d-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]alanine
• Sodium dextrothyroxine
• Thyroxine, monosodium salt, <span class="text-smallcaps">D</span>-
• Travenon
• sodium (2R)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
• Thyroxine, monosodium salt, D-
• D-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt

Dextrothyroxine sodium

CAS: 137-53-1

Dextrothyroxine sodium is the dextrorotary isomer of thyroxine.

Formula: C₁₅H₁₀I₄NNaO₄

Color and Shape: Solid

Molecular weight: 798.85

Ref: TM-T21383L

D-Thyroxine sodium salt

CAS: 137-53-1

D-Thyroxine sodium salt is a drug that is used for the treatment of hypothyroidism. It has been shown to increase the metabolic rate and cardiac output in humans, as well as having long-term efficacy. D-Thyroxine sodium salt inhibits the conversion of T4 to T3 by inhibiting 5'-deiodinase, leading to increased levels of T4. This drug also increases the thermogenic rate and energy expenditure by stimulating brown adipose tissue, which leads to an increase in oxygen consumption and heat production. D-Thyroxine sodium salt has a number of side effects, including cardiac arrhythmia, hyperthyroidism, insomnia, and gastrointestinal disturbances.
D-Thyroxine sodium salt is a chiral compound consisting of two enantiomers: levothyroxine (L) and dextrothyroxine (D). The L form is biologically active while the D form is biologically inactive.

Formula: C₁₅H₁₀I₄NO₄Na

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 798.85 g/mol

Ref: 3D-FT66812