CAS 137017-45-9

Cytidine, 2'-deoxy-5-formyl-

CAS: 137017-45-9

Formula: C₁₀H₁₃N₃O₅

Purity: 98%

Molecular weight: 255.2273

Ref: IN-DA0012PF

4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde

CAS: 137017-45-9

4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde

Purity: 98%

Molecular weight: 255.23g/mol

Ref: 54-OR1062323

2''-Deoxy-5-formylcytidine

CAS: 137017-45-9

Formula: C₁₀H₁₃N₃O₅

Purity: ≥ 98.0%

Color and Shape: White to off-white solid

Molecular weight: 255.23

Ref: 7W-GW1127

2'-Deoxy-5-formyl-cytidine

Controlled Product

CAS: 137017-45-9

Applications 2'-Deoxy-5-formyl-cytidine is a nucleotide derivative found in embryonic stem cell DNA.
References Pfaffeneder, T., et al.: Angew. Chem. Int. Edit., 50, 7008-7012 (2011)

Formula: C₁₀H₁₃N₃O₅

Color and Shape: Neat

Molecular weight: 255.227

Ref: TR-D239810

2'-Deoxy-5-formylcytidine

CAS: 137017-45-9

2'-Deoxy-5-formylcytidine is a nucleoside analog that is used as a chemotherapeutic agent. It is cytotoxic to cells by binding to DNA and preventing the synthesis of DNA, RNA, and protein. The drug has been shown to induce cellular senescence in human fibroblasts, which can be reversed by the addition of deuterium. 2'-Deoxy-5-formylcytidine also inhibits the production of reactive oxygen species (ROS) by inducing the expression of antioxidant enzymes such as superoxide dismutase 2 and glutathione peroxidase 1. The oxidation products are misincorporated into DNA strands, leading to intramolecular hydrogen bonds with cytosine bases. These modifications lead to denaturation of DNA and inhibition of transcription and replication.
2'-Deoxy-5-formylcytidine also interacts with oligodeoxynucleotides, which leads to misinc

Formula: C₁₀H₁₃N₃O₅

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 255.23 g/mol

Ref: 3D-ND63556

2'-Deoxy-5-formyl-cytidine-1,3-15N2,2-13C

Controlled Product

CAS: 137017-45-9

Formula: CC₉H₁₃₁₅N₂NO₅

Color and Shape: Neat

Molecular weight: 258.207

Ref: TR-D239812