CAS 137061-46-2

nisin Z

Description:

Nisin Z is a naturally occurring antimicrobial peptide that belongs to the class of lantibiotics, which are produced by certain strains of the bacterium Lactococcus lactis. It is characterized by its ability to inhibit the growth of a wide range of Gram-positive bacteria, including pathogens such as Listeria monocytogenes. Nisin Z is composed of a sequence of amino acids that includes several unusual residues, such as lanthionine and methyllanthionine, which contribute to its stability and activity. This peptide is commonly used as a food preservative due to its effectiveness in extending shelf life and ensuring food safety. It operates by binding to lipid II, a key component in bacterial cell wall synthesis, ultimately disrupting cell wall formation and leading to cell death. Nisin Z is recognized as safe for consumption and is approved for use in various food products. Its unique structure and mechanism of action make it a valuable tool in both food preservation and potential therapeutic applications against antibiotic-resistant bacteria.

Formula: C₁₄₁H₂₂₉N₄₁O₃₈S₇

Synonyms:

• Nisin Z

Nisin Z

CAS: 137061-46-2

Formula: C₁₄₁H₂₂₉N₄₁O₃₈S₇

Color and Shape: Solid

Molecular weight: 3331.0339

Ref: IN-DA00A8YJ

Nisin Z

CAS: 137061-46-2

Nisin Z has anti-inflammatory activity and reduces the release of pro-inflammatory cytokines.

Formula: C₁₄₁H₂₂₉N₄₁O₃₈S₇

Color and Shape: Solid

Molecular weight: 3331.03

Ref: TM-T76264

Nisin Z (~80%) Hydrochloride

CAS: 137061-46-2

Applications Nisin Z Hydrochloride is a peptide antibiotic synthesized by Lactococcus lactis. Nisin Z interacts with lipid II, a lipid component of cell wall, to form pores in the plasma membrane.
References Kuipers, O. P., et al.: J. Biol. Chem. 270, 27299 (1995); Breukink, E., et al.: Science 286, 2361 (1999); Breukink, E., et al.: Biochemistry 36, 6968 (1997)

Formula: C₁₄₁H₂₂₉N₄₁O₃₈S₇·x(HCl)

Color and Shape: Neat

Molecular weight: 3331.033646

Ref: TR-N487558