CAS 137076-22-3

1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

Description:

1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde, with the CAS number 137076-22-3, is a chemical compound characterized by its functional groups and structural features. It contains a piperidine ring, which is a six-membered nitrogen-containing heterocycle, and an aldehyde functional group, indicating its potential reactivity in various chemical reactions, particularly in nucleophilic additions. The tert-butoxycarbonyl (Boc) group serves as a protective group for amines, enhancing the compound's utility in organic synthesis, especially in peptide chemistry. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and specific conditions. Its solubility is generally good in organic solvents, making it suitable for various applications in synthetic organic chemistry. The presence of both the Boc and aldehyde functionalities allows for diverse reactivity, including potential coupling reactions and further transformations. Overall, 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde is a valuable intermediate in the synthesis of more complex organic molecules.

Formula: C₁₁H₁₉NO₃

InChI: InChI=1/C11H19NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h8-9H,4-7H2,1-3H3

SMILES: CC(C)(C)OC(=O)N1CCC(CC1)C=O

Synonyms:

• 4-Formyl-Piperidine-1-Carboxylic Acid Tert-Butyl Ester
• 1-Boc-4-Piperidinecarboxaldehyde
• 1-Boc-4-Formylpiperidine
• 1-Tert-Butoxycarbonylpiperidine-4-Carboxyl Aldehyde
• 1-N-Boc-4-Formylpiperidine
• N-Boc-4-Piperidinylcarboxaldehyde
• N-Boc-4-Formylpiperidine
• 1-N-Boc-4-piperidinecarboxaldehyde
• 1-Piperidinecarboxylic acid, 4-formyl-, 1,1-dimethylethyl ester
• Tert-Butyl 4-Formylpiperidine-1-Carboxylate
• N-BOC-4-piperidinecarboxaldehyde
• N-BOC-4-piperidine carboxaldehyde
• N-BOC-4-piperidine carboxyaldehyde

1-(tert-Butoxycarbonyl)-4-piperidinecarboxaldehyde

CAS: 137076-22-3

Formula: C₁₁H₁₉NO₃

Purity: >95.0%(GC)

Color and Shape: White or Colorless to Light yellow powder to lump to clear liquid

Molecular weight: 213.28

Ref: 3B-B3873

1-Boc-piperidine-4-carboxaldehyde, 97%

CAS: 137076-22-3

1-Boc-piperidine-4-carboxaldehyde is used as reactant for synthesis of Pim-1 inhibitors, selective GPR119 agonists for type II diabetes, M-tropic (R5) HIV-1 replication inhibitors, HDAC inhibitors and selective 5-HT6 antagonists. It is also used as reactant for three-component vinylogous Mannich re

Formula: C₁₁H₁₉NO₃

Purity: 97%

Color and Shape: Crystals, White to off-white

Molecular weight: 213.28

Ref: 02-H52813

N-Boc-4-Formylpiperidine

CAS: 137076-22-3

Formula: C₁₁H₁₉NO₃

Purity: 97%

Color and Shape: Liquid

Molecular weight: 213.2735

Ref: IN-DA0035CP

Piperidine-4-carboxaldehyde, N-BOC protected

CAS: 137076-22-3

Piperidine-4-carboxaldehyde, N-BOC protected

Formula: C₁₁H₁₉NO₃

Purity: 97%

Color and Shape: off-white to yellow low melting fused solid

Molecular weight: 213.27g/mol

Ref: 54-OR13630

1-Boc-4-formylpiperidine

CAS: 137076-22-3

Purity: 97%

Molecular weight: 213.273

Ref: FT-B13566

N-Boc-4-Piperidinecarboxaldehyde

CAS: 137076-22-3

Formula: C₁₁H₁₉NO₃

Purity: 97%

Color and Shape: Solid, Crystalline Powder or Granules

Molecular weight: 213.277

Ref: 10-F038576

4-Formylpiperidine-1-carboxylic Acid tert-Butyl Ester

Controlled Product

CAS: 137076-22-3

Applications An intermediate for polycyclic indazole derivatives that are ERK inhibitors.
References Orjales, A., et al.: J. Med. Chem., 46, 5512 (2003), Mariappan, P., et al.: J. Eur. Urology., 51, 67 (2007), Hughes, J., et al.: Bioorg. Med. Chem. Lett., 18, 4872 (2008), Kielbasa, W., et al.: Drug Metab. Dispos., 37, 137 (2009),

Formula: C₁₁H₁₉NO₃

Color and Shape: Neat

Molecular weight: 213.27

Ref: TR-F700925

1-Boc-4-formyl piperidine

CAS: 137076-22-3

The functional theory of 1-Boc-4-formyl piperidine (1BP) is that it activates the serine protease, which in turn inhibits the acetylcholine release. It also affects the 5-ht4 receptor, which is an important regulator of neuronal function and amine release. 1BP has been shown to have potent inhibitory activity against reactive molecules, including those that are involved in carcinogenesis. It also has a high affinity for the 5-ht4 receptor and can be used as a 5-ht4 receptor agonist.

Formula: C₁₁H₁₉NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 213.27 g/mol

Ref: 3D-FB12557