CAS 1371638-05-9

Quetiapine Impurity E

Description:

Quetiapine Impurity E, identified by its CAS number 1371638-05-9, is a chemical compound that is recognized as an impurity associated with the antipsychotic medication quetiapine. This substance is typically characterized by its molecular structure, which may include specific functional groups that differentiate it from the parent compound. Impurities like Quetiapine Impurity E can arise during the synthesis of pharmaceuticals and may affect the overall purity and efficacy of the final product. The presence of such impurities is closely monitored in pharmaceutical manufacturing due to potential impacts on safety and therapeutic outcomes. Quetiapine itself is primarily used to treat conditions such as schizophrenia and bipolar disorder, and the identification and quantification of impurities like Quetiapine Impurity E are essential for ensuring compliance with regulatory standards. Analytical techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry are commonly employed to detect and characterize such impurities in pharmaceutical formulations.

Formula: C₄₀H₄₄N₆O₂S₂

Synonyms:

• Quetiapine Impurity E 4HCl
• Quetiapine Impurity 23
• Quetiapine EP Impurity E (base))
• Quetiapine EP Impurity E
• Quetiapine Impurity 6(Quetiapine EP Impurity E)
• Quetiapine Fumarate EP Impurity E
• 1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane
• 1,2-bis(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethane tetrahydrochloride
• 1,2-bis(2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethane
• 11,11'-[ethylenebis(oxyethylenepiperazine-4,1-diyl)]bis(dibenzo[b,f][1,4]thiazepine)(Quetiapine EP Impurity E）
• Quetiapine EP Impurity E/Quetiapine bis-Ether

1,2-bis(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethane

CAS: 1371638-05-9

Formula: C₄₀H₄₄N₆O₂S₂

Color and Shape: Solid

Molecular weight: 704.9464

Ref: IN-DA0012W2

Quetiapine EP Impurity E

CAS: 1371638-05-9

Formula: C₄₀H₄₄N₆O₂S₂

Molecular weight: 704.95

Ref: 4Z-Q-0112

Quetiapine EP Impurity E

CAS: 1371638-05-9

Formula: C₄₀H₄₄N₆O₂S₂

Molecular weight: 704.95

Ref: ST-EA-CP-Q1005

1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane

Controlled Product

CAS: 1371638-05-9

Impurity Quetiapine EP Impurity E
Applications 1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane (Quetiapine EP Impurity E) is an impurity of Quetiapine (Q510000), an atypical antipsychotic agent used for the treatment of patients with schizophrenia, biopolar disorder and to treat major depressive disorder.
References Kumar, K., et al.: Org. Chem. Indian. J., 8, 164 (2012);

Formula: C₄₀H₄₄N₆O₂S₂

Color and Shape: Neat

Molecular weight: 704.95

Ref: TR-B419120

1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane-d16

Controlled Product

CAS: 1371638-05-9

Applications Isotope labelled 1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane is an impurity of Quetiapine (Q510000), an atypical antipsychotic agent used for the treatment of patients with schizophrenia, biopolar disorder and to treat major depressive disorder.
References Kumar, K., et al.: Org. Chem. Indian. J., 8, 164 (2012);

Formula: C₄₀D₁₆H₂₈N₆O₂S₂

Color and Shape: Neat

Molecular weight: 721.045

Ref: TR-B419122