CAS 137174-25-5

Budesonide Related Compound G (16α,17-[butylidenebis(oxy)]-11β, 21-dihydroxypregna-4-ene-3,20-dione)

CAS: 137174-25-5

Adrenal cortical hormones and their derivatives nesoi

Formula: C₂₅H₃₆O₆

Color and Shape: Off-White Powder

Molecular weight: 432.25119

Ref: 45-1078267

Budesonide EP Impurity G (Budesonide USP Related Compound G, 1,2-Dihydro Budesonide) (Mixture of Diastereomers)

CAS: 137174-25-5

Formula: C₂₅H₃₆O₆

Color and Shape: White To Off-White Solid

Molecular weight: 432.56

Ref: 4Z-B-0312

16α,17-[(1RS)-Butylidenebis(oxy)]-11β,21-dihydroxypregn-4-ene-3,20-dione (1,2-Dihydrobudesonide)

CAS: 137174-25-5

Formula: C₂₅H₃₆O₆

Color and Shape: Neat

Molecular weight: 432.55

Ref: 86-MM0204.07

1,2-Dihydrobudesonide (Mixture of diastereomers)

Controlled Product

CAS: 137174-25-5

Impurity Budesonide EP Impurity G
Applications 1,2-Dehydrobudesonide (Budesonide EP Impurity G) is an impurity in the synthesis of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.
References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),

Formula: C₂₅H₃₆O₆

Color and Shape: Neat

Molecular weight: 432.55

Ref: TR-D229330

1,2-Dihydrobudesonide-d8

Controlled Product

CAS: 137174-25-5

Formula: C₂₅D₈H₂₈O₆

Color and Shape: Neat

Molecular weight: 440.599

Ref: TR-D229332

1,2-Dihydrobudesonide

CAS: 137174-25-5

1,2-Dihydrobudesonide is a synthetic glucocorticosteroid that has a molecular structure similar to prednisolone. It is used for the treatment of inflammatory skin conditions such as eczema and psoriasis. 1,2-Dihydrobudesonide has been shown to have a high oral bioavailability and low systemic bioavailability. The molecule is metabolized in the liver to produce hydrocortisone, which accounts for its oral bioavailability. 1,2-Dihydrobudesonide is classified as an acetal because it contains an acetal linkage between the 16-carbon (C16) steroid nucleus and the 17-carbon (C17) side chain. This connection results in a more stable molecule than desonide, which is not acetalated. In vitro data indicates that 1,2-dihydrobudesonide has a lower binding affinity with human liver cytosolic receptors than des

Formula: C₂₅H₃₆O₆

Purity: Min. 95%

Molecular weight: 432.55 g/mol

Ref: 3D-FD146154

Budesonide EP Impurity G

CAS: 137174-25-5

Formula: C₂₅H₃₆O₆

Molecular weight: 432.56

Ref: ST-EA-CP-B19007