CAS 137234-88-9

4-Ethyl-5-fluoropyrimidine

Description:

4-Ethyl-5-fluoropyrimidine is a heterocyclic organic compound characterized by a pyrimidine ring substituted with an ethyl group at the 4-position and a fluorine atom at the 5-position. This compound typically exhibits a pale yellow to colorless appearance and is soluble in polar organic solvents. Its molecular structure contributes to its potential applications in pharmaceuticals, particularly in the development of antiviral and anticancer agents, due to the presence of the fluorine atom which can enhance biological activity and lipophilicity. The compound's reactivity is influenced by the electron-withdrawing nature of the fluorine substituent, which can affect nucleophilic attack and other chemical interactions. Additionally, 4-Ethyl-5-fluoropyrimidine may undergo various reactions typical of pyrimidine derivatives, such as alkylation, acylation, and substitution reactions, making it a versatile intermediate in organic synthesis. Safety data should be consulted for handling and storage, as with all chemical substances, to ensure proper laboratory practices.

Formula: C₆H₇FN₂

InChI: InChI=1S/C6H7FN2/c1-2-6-5(7)3-8-4-9-6/h3-4H,2H2,1H3

InChI key: InChIKey=AYZDRTRWCASUFO-UHFFFAOYSA-N

SMILES: C(C)C=1C(F)=CN=CN1

Synonyms:

• 4-Ethyl-3-Fluoropyridine
• 4-Ethyl-5-Fluoropyri
• 4-Ethyl-5-Fluoropyrimidine
• Pyrimidine, 4-ethyl-5-fluoro-
• Pyrimidine, 4-ethyl-5-fluoro- (9CI)
• Ubidearenone

Pyrimidine, 4-ethyl-5-fluoro-

CAS: 137234-88-9

Formula: C₆H₇FN₂

Purity: 97%

Color and Shape: Liquid

Molecular weight: 126.1316

Ref: IN-DA0012ZX

Voriconazole EP Impurity C

CAS: 137234-88-9

Formula: C₆H₇FN₂

Color and Shape: Colourless Liquid

Molecular weight: 126.13

Ref: 4Z-V-105

4-Ethyl-5-fluoropyrimidine

CAS: 137234-88-9

4-Ethyl-5-fluoropyrimidine

Purity: 97%

Molecular weight: 126.13g/mol

Ref: 54-PC1837

4-Ethyl-5-fluoropyrimidine

CAS: 137234-88-9

Color and Shape: Neat

Ref: 86-MM1094.06

4-Ethyl-5-fluoropyrimidine

CAS: 137234-88-9

Impurity Voriconazole EP Impurity C
Stability Volatile
Applications 4-Ethyl-5-fluoropyrimidine (Voriconazole EP Impurity C) is a Voriconazole (V760000) impurity.
References Miletic, T. et al.: Carb. polym., 98, 122 (2013); Rieke, R., et al.: Science, 246, 1260 (1989), Dickinson, R., et al.: Bioorg. Med. Chem. Lett., 6, 2031 (1996),

Formula: C₆H₇FN₂

Color and Shape: Neat

Molecular weight: 126.13

Ref: TR-E918001

Voriconazole EP Impurity C

CAS: 137234-88-9

Formula: C₆H₇FN₂

Molecular weight: 126.13

Ref: ST-EA-CP-V13003

4-Ethyl-5-fluoropyrimidine

CAS: 137234-88-9

Formula: C₆H₇FN₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 126.134

Ref: 10-F079955

4-Ethyl-5-fluoropyrimidine

CAS: 137234-88-9

4-Ethyl-5-fluoropyrimidine is a white solid with a melting point of 258°C. It is soluble in organic solvents such as acetonitrile and methanol. The compound has been shown to have reversed phase chromatographic properties and can be used as a potential impurity in the synthesis of other compounds. 4-Ethyl-5-fluoropyrimidine is not susceptible to photolytic decomposition but can be oxidized by air, which may result in the formation of impurities. 4-Ethyl-5-fluoropyrimidine can be purified using chromatography methods with high sensitivity and low detection limits. The compound has also been shown to have good chemical stability under ambient conditions, making it suitable for storage or shipping.

Formula: C₆H₇FN₂

Purity: Min. 95%

Molecular weight: 126.13 g/mol

Ref: 3D-FE77839