CAS 13726-69-7

1-(1,1-Dimethylethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate

Description:

1-(1,1-Dimethylethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate, with CAS number 13726-69-7, is a chemical compound characterized by its pyrrolidine structure, which features two carboxylate groups and a hydroxyl group. This compound is a derivative of pyrrolidine, a five-membered nitrogen-containing heterocycle, and is notable for its stereochemistry, specifically the (2S,4R) configuration, which indicates the spatial arrangement of its substituents. The presence of the tert-butyl group (1,1-dimethylethyl) contributes to its hydrophobic characteristics, influencing its solubility and reactivity. The hydroxyl group enhances its potential for hydrogen bonding, which can affect its interactions in biological systems. This compound may be of interest in medicinal chemistry and organic synthesis due to its structural features, which could impart specific biological activities or serve as intermediates in the synthesis of more complex molecules. As with many organic compounds, its stability, reactivity, and potential applications would depend on the specific conditions under which it is used.

Formula: C₁₀H₁₇NO₅

InChI: InChI=1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7+/m1/s1

InChI key: InChIKey=BENKAPCDIOILGV-RQJHMYQMSA-N

SMILES: C(OC(C)(C)C)(=O)N1[C@H](C(O)=O)C[C@@H](O)C1

Synonyms:

• (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
• (2S,4R)-1-(tertbutoxycarbonyl)-4-hydroxypyrrolidine carboxylic acid
• (2S,4R)-1-Boc-4-Hydroxy-Proline
• (2S,4R)-4-Hydroxy-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid
• (2S,4R)-4-Hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
• (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
• (2S,4R)-4-hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
• (2S,4R)-N-tert-Butoxycarbonyl-4-hydroxyproline
• (4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline
• 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) ester, (2S,4R)-
• 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) ester, (2S-trans)-
• 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-tert-butyl ester, <span class="text-smallcaps">L</span>-
• 1-(1,1-Dimethylethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
• 1-(Tert-Butoxycarbonyl)-4-Hydroxyproline
• 1-(tert-Butoxycarbonyl)-(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
• 4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
• BOC-4-Hydroxy-L-Proline
• Boc-<span class="text-smallcaps">L</span>-trans-γ-hydroxyproline
• Boc-Hyp-OH
• Boc-L-Hyp-OHN-(tert-Butoxycarbonyl)-L-4-hydroxyproline
• Boc-trans-4-hydroxy-L-proline
• Boc-trans-Hydroxy-<span class="text-smallcaps">L</span>-proline
• N-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• N-(tert-Butoxycarbonyl)hydroxy-<span class="text-smallcaps">L</span>-proline
• N-(tert-Butoxycarbonyl)hydroxyproline
• N-(tert-Butyloxycarbonyl)-4-hydroxyproline
• N-BOC-trans-4-hydroxy-L-proline
• N-Boc-trans-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• N-T-bocl-hydroxyproline
• N-tert-Butoxycarbonyl trans-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• N-tert-Butoxycarbonyl-(4R)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• NSC 343720
• trans-1-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-tert-butyl ester, L-

trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline

CAS: 13726-69-7

Formula: C₁₀H₁₇NO₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 231.25

Ref: 3B-B1635

N-Boc-trans-4-hydroxy-L-proline, 97%

CAS: 13726-69-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₇NO₅

Purity: 97%

Color and Shape: White, Powder

Molecular weight: 231.25

Ref: 02-H27110

N-Boc-(2S,4R)-4-hydroxyproline

CAS: 13726-69-7

Formula: C₁₀H₁₇NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 231.2457

Ref: IN-DA0034K2

(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, N-BOC protected

CAS: 13726-69-7

(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, N-BOC protected

Formula: C₁₀H₁₇NO₅

Purity: 97%

Color and Shape: white/off white crystalline powder

Molecular weight: 231.24567g/mol

Ref: 54-OR307069

Boc-Hyp-OH

CAS: 13726-69-7

Formula: C₁₀H₁₇NO₅

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 231.25

Ref: 7W-GM8684

Boc-L-Hydroxyproline

CAS: 13726-69-7

Formula: C₁₀H₁₇NO₅

Molecular weight: 231.25

Ref: 4Z-P-166029

Boc-Hyp-OH

CAS: 13726-69-7

M03213 - Boc-Hyp-OH

Formula: C₁₀H₁₇NO₅

Purity: 97%

Color and Shape: Crystalline Powder,Powder

Molecular weight: 231.248

Ref: 10-M03213

BOC-L-Hydroxyproline extrapure, 98%

CAS: 13726-69-7

Formula: C₁₀H₁₇NO₅

Purity: min 98%

Color and Shape: White to off white, Crystalline powder

Molecular weight: 231.25

Ref: SR-38544

Boc-trans-Hydroxy-L-proline

Controlled Product

CAS: 13726-69-7

Applications boc-trans-Hydroxy-L-proline is used in the preparation of hydroxyproline derivatives. boc-trans-Hydroxy-L-proline is an intermediate in the synthesis of Fosinopril-d5 Sodium Salt (F727803), the labeled analogue of Fosinopril Sodium Salt (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
References Nakanishi, K., et. al.: Peptide Sci., 47, 197 (2010); Singhvi, S.M., et al.: Br. J. Clin. Pharmacol., 25, 9 (1988); Sullivan, P.A., et al.: Am. J. Hypertension, 1, 280S (1988)

Formula: C₁₀H₁₇NO₅

Color and Shape: Neat

Molecular weight: 231.25

Ref: TR-H952495