CAS: 137281-23-3 - N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid

Formula: C₂₀H₂₁N₅O₆

InChI: InChI=1S/C20H21N5O6/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29)/t13-/m0/s1

InChI key: InChIKey=WBXPDJSOTKVWSJ-ZDUSSCGKSA-N

SMILES: O=C1N=C(N)NC=2NC=C(C12)CCC3=CC=C(C=C3)C(=O)NC(C(=O)O)CCC(=O)O

Synonyms:

• (S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid
• 1H-Pyrrolo[2,3-d]pyrimidine, <span class="text-smallcaps">L</span>-glutamic acid deriv.
• 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H pyrodo[2,3-d]Pyrimidin-5-yl)ethyl]-benzoic Acid
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-
• L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-
• N-(4-(2-(2-Amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid
• N-(4-[2-(2-Amino-4,7-Dihydro-4-oxo-1H-pyrrolo)[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-Gluamic Acid
• N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid
• N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid
• N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]L-Glutamic acid
• N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid
• NSC 698037
• Pefloxacinmesylate Pharma-0549
• Pemetrexed
• Pemetrexed Acid
• disodium (2R)-2-({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}amino)pentanedioate

Pemetrexed

CAS: 137281-23-31916503-69-9

• Formula: C₂₀H₂₁N₅O₆
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Blue powder to crystal
• Molecular weight: 427.42

L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-

CAS: 137281-23-3

• Formula: C₂₀H₂₁N₅O₆
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 427.4106

Pemetrexed

CAS: 137281-23-3

Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate …

• Formula: C₂₀H₂₁N₅O₆
• Purity: 100% - 99.96%
• Color and Shape: Similar To White Powder
• Molecular weight: 427.41

Pemetrexed

CAS: 137281-23-3

• Formula: C₂₀H₂₁N₅O₆
• Color and Shape: White To Off-White Solid
• Molecular weight: 427.42

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid

CAS: 137281-23-3

Applications N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid, referred to as Pemetrexed, is used in the treatment of malignant pleural …

• Formula: C₂₀H₂₁N₅O₆
• Color and Shape: Neat
• Molecular weight: 427.41

(S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid

CAS: 137281-23-3

• Purity: 95.0%
• Color and Shape: Solid, Blue powder
• Molecular weight: 427.4169921875

Pemetrexed - Bio-X ™

CAS: 137281-23-3

Pemetrexed is a chemotherapy drug that belongs to the class of drugs called folate antimetabolites. …

• Formula: C₂₀H₂₁N₅O₆
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 427.41 g/mol

Pemetrexed

CAS: 137281-23-3

Thymidylate synthase inhibitor; antifolate antineoplastic agent

• Formula: C₂₀H₂₁N₅O₆
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 427.41 g/mol