
CAS 1373038-60-8
:Valdecoxib IMpurity B
Description:
Valdecoxib Impurity B, identified by its CAS number 1373038-60-8, is a chemical compound associated with the pharmaceutical agent valdecoxib, a selective COX-2 inhibitor used for pain relief and anti-inflammatory purposes. As an impurity, it may arise during the synthesis or degradation of valdecoxib and is typically characterized by its molecular structure, which may differ slightly from the parent compound. Impurities like Valdecoxib Impurity B are often assessed for their potential impact on the safety and efficacy of the drug. The characteristics of such impurities can include their solubility, stability, and reactivity, which are crucial for understanding their behavior in pharmaceutical formulations. Analytical techniques such as HPLC (High-Performance Liquid Chromatography) and mass spectrometry are commonly employed to identify and quantify impurities in drug substances. Regulatory guidelines necessitate the characterization and control of impurities to ensure the quality and safety of pharmaceutical products.
Formula:C32H25N3O6S2
Synonyms:- 4-(5-Methyl-3-phenylisoxazol-4-yl)-N-((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)benzenesulfonamide (Palbociclib Impurity)
- Valdecoxib DiMer,Valdecoxib IMpurity B
- Parecoxib Impurity 13
- BenzenesulfonaMide, 4-(5-Methyl-3-phenyl-4-isoxazolyl)-N-[[4-(5-Methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-
- 4-(5-methyl-3-phenylisoxazol-4-yl)-N-((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)benzenesulfonamide
- 4-(5-methyl-3-phenylisoxazol-4-yl)-N-((4-(5-
- Parecoxib impurity 6/Valdecoxib Dimer/4-(5-methyl-3-phenylisoxazol-4-yl)-N-((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)benzenesulfonamide
- Valdecoxib DiMer
- Valdecoxib IMpurity B
- Parecoxib Sodium Impurity 13
- (Valdecoxib IMpurity B)
- N-[4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl]-4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonaMide
- 4-(5-Methyl-3-phenyl-4-isoxazolyl)-N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]benzenesulfonamide
- methyl-3-phenylisoxazol-4-yl)phenyl)
- Parecoxib-006
- sulfonyl)benzenesulfonamide sodium
- Valdecoxib IMpurity L
- See more synonyms
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Found 7 products.
Valdecoxib Impurity 9
CAS:Formula:C32H25N3O6S2Color and Shape:White To Off-White SolidMolecular weight:611.694-(5-Methyl-3-phenylisoxazol-4-yl)-N-((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)benzenesulfonamide (Palbociclib Impurity)
CAS:<p>4-(5-Methyl-3-phenylisoxazol-4-yl)-N-((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)benzenesulfonamide (Palbociclib Impurity)</p>Purity:98%Molecular weight:611.69g/mol4-(5-METHYL-3-PHENYLISOXAZOL-4-YL)-N-((4-(5-METHYL-3-PHENYLISOXAZOL-4-YL)PHENYL)SULFONYL)BENZENESULFONAMIDE
CAS:Purity:97%Molecular weight:611.6900024414062Valdecoxib Dimer
CAS:Controlled Product<p>Applications Valdecoxib Dimer is a dimeric impurity of the cyclooxygenase-2 inhibitor, Valdecoxib (V090000).<br></p>Formula:C32H25N3O6S2Color and Shape:NeatMolecular weight:611.69Valdecoxib dimer
CAS:<p>Valdecoxib dimer is a drug product that has been custom synthesized to meet the customer's requirements. It is an analytical standard and is available in high purity. Valdecoxib dimer has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Valdecoxib dimer also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture. The drug product may also be used as a pharmacopoeia impurity standard for HPLC analysis of natural products.</p>Formula:C32H25N3O6S2Purity:Min. 95%Molecular weight:611.7 g/mol







