CAS 137328-52-0

(8β)-N-[(1S,2R)-2-Hydroxycyclopentyl]-6-methyl-1-(1-methylethyl)ergoline-8-carboxamide

Description:

The chemical substance known as (8β)-N-[(1S,2R)-2-Hydroxycyclopentyl]-6-methyl-1-(1-methylethyl)ergoline-8-carboxamide, with the CAS number 137328-52-0, is a synthetic derivative of ergoline, a class of compounds that includes various alkaloids. This compound features a complex structure characterized by a bicyclic ergoline backbone, which is modified with a hydroxyl group and a carboxamide functional group. The presence of the cyclopentyl moiety and the specific stereochemistry indicated by the (1S,2R) configuration contributes to its potential biological activity. Such modifications can influence the compound's pharmacological properties, including receptor binding affinity and selectivity. Compounds of this nature are often studied for their potential therapeutic applications, particularly in the fields of neurology and psychiatry, due to their interactions with neurotransmitter systems. However, detailed studies on its specific biological effects, safety profile, and therapeutic potential would be necessary to fully understand its characteristics and applications.

Formula: C₂₄H₃₃N₃O₂

InChI: InChI=1S/C24H33N3O2/c1-14(2)27-13-15-11-21-18(17-6-4-8-20(27)23(15)17)10-16(12-26(21)3)24(29)25-19-7-5-9-22(19)28/h4,6,8,13-14,16,18-19,21-22,28H,5,7,9-12H2,1-3H3,(H,25,29)/t16-,18-,19+,21-,22-/m1/s1

InChI key: InChIKey=IMSDOBUYDTVEHN-ILMFXRJHSA-N

SMILES: C(C)(C)N1C2=C3C([C@@]4([C@@](CC3=C1)(N(C)C[C@H](C(N[C@@H]5[C@H](O)CCC5)=O)C4)[H])[H])=CC=C2

Synonyms:

• LY 215840
• (8β)-N-[(1S,2R)-2-Hydroxycyclopentyl]-6-methyl-1-(1-methylethyl)ergoline-8-carboxamide
• Ergoline-8-carboxamide, N-[(1S,2R)-2-hydroxycyclopentyl]-6-methyl-1-(1-methylethyl)-, (8β)-
• Ergoline-8-carboxamide, N-(2-hydroxycyclopentyl)-6-methyl-1-(1-methylethyl)-, [8β(1S,2R)]-

LY 215840

CAS: 137328-52-0

LY 215840 is a cyclase inhibitor that blocks the conversion of 5-hydroxytryptamine (5-HT) to serotonin, which is the final step in the synthesis of this neurotransmitter. LY 215840 has been shown to have glomerulosa activity and can be used in the treatment of thyroid disease and piperazine. LY 215840 also has atypical properties and can be used for the treatment of depression and anxiety disorders. It also has antagonistic effects on 5-ht4 receptors, which leads to an increase in serotonin levels in cells. LY 215840 also has an antagonist effect on melanocortin receptors, which leads to decreased appetite and weight loss.

Formula: C₂₄H₃₃N₃O₂

Purity: Min. 95%

Molecular weight: 395.5 g/mol

Ref: 3D-MFA32852

LY 215840

CAS: 137328-52-0

5-HT2/5-HT7 receptor antagonist

Formula: C₂₄H₃₃N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 395.54

Ref: TM-T22940