CAS 137330-13-3

Tilmicosin phosphate

Description:

Tilmicosin phosphate is a semi-synthetic macrolide antibiotic primarily used in veterinary medicine, particularly for the treatment of respiratory infections in livestock. It is derived from the natural product tylosin and exhibits broad-spectrum activity against various Gram-positive bacteria and some Gram-negative bacteria. The compound functions by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of pathogens. Tilmicosin is known for its lipophilicity, which allows it to penetrate bacterial cell membranes effectively. It is typically administered via injection or in feed formulations. The substance has a relatively long half-life, enabling sustained therapeutic effects. However, it is important to note that tilmicosin can be toxic to certain animal species, particularly horses and humans, leading to potential safety concerns. As with all antibiotics, the use of tilmicosin should be managed carefully to mitigate the risk of developing antibiotic resistance. Its chemical structure includes a phosphate group, which enhances its solubility and stability in various formulations.

Formula: C₂₀H₂₂N₂O₄

InChI: InChI=1/C20H22N2O4/c1-12-5-6-15-10-16-9-14(7-8-17(16)26-19(15)21-12)13(2)20(24)25-11-18(23)22(3)4/h5-9,13H,10-11H2,1-4H3/t13-/m1/s1

SMILES: Cc1ccc2Cc3cc(ccc3Oc2n1)[C@@H](C)C(=O)OCC(=O)N(C)C

Synonyms:

• 20-Deoxo-20-(3,5-Dimethyl-1-Piperidinyl)Desmycosin Phosphate
• Tilmicosina Fosfato
• 2-(dimethylamino)-2-oxoethyl (2R)-2-(2-methyl-5H-chromeno[2,3-b]pyridin-7-yl)propanoate
• Timicosin Phosphate

Tilmicosin phosphate

CAS: 137330-13-3

Formula: C₄₆H₈₃N₂O₁₇P

Purity: 95%

Color and Shape: Solid

Molecular weight: 967.1282

Ref: IN-DA00HUXF

Tilmicosin phosphate

CAS: 137330-13-3

Tilmicosin phosphate

Purity: ≥95%

Molecular weight: 967.1g/mol

Ref: 54-BUP16686

Tilmicosin phosphate salt

CAS: 137330-13-3

Formula: C₄₆H₈₀N₂O₁₃·H₃PO₄

Purity: ≥ 75.0% (dried basis)

Color and Shape: White to off-white powder

Molecular weight: 967.13

Ref: 7W-GA7223

Tilmicosin phosphate

CAS: 137330-13-3

Tilmicosin phosphate, a macrolide antibiotic, is used to treat cattle for pathogens that cause Bovine Respiratory Disease.

Formula: C₄₆H₈₃N₂O₁₇P

Purity: 95.29% - 97.13%

Color and Shape: Light Yellow Powder

Molecular weight: 967.1

Ref: TM-T22439

Tilmicosin Phosphate

CAS: 137330-13-3

Formula: C₄₆H₈₀N₂O₁₃·H₃O₄P

Molecular weight: 869.15 97.99

Ref: 4Z-T-193005

Tilmicosin Phosphate Salt (~80%)

CAS: 137330-13-3

Applications Tilmicosin Phosphate Salt is the phosphate salt of the semi-synthetic antibiotic derivative. It can be used in biological study and pharmacological activity of bactericidal effects of various concentrations of enrofloxacin, florfenicol, tilmicosin phosphate, and tulathromycin on clinical isolates of Mannheimia haemolytica from cattle.
References Blondeau, J., et al.: Am J Vet Res, 76, 860 (2015)

Formula: C₄₆H₈₀N₂O₁₃·H₃O₄P

Purity: ~80%

Color and Shape: Neat

Molecular weight: 967.13

Ref: TR-T440503

Tilmicosin phosphate

Controlled Product

CAS: 137330-13-3

Tilmicosin phosphate is a phosphate salt form of tilmicosin with similar action and applications as tilmicosin.

Formula: C₄₆H₈₀N₂O₁₃·H₃PO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 967.13 g/mol

Ref: 3D-AT31128