CAS 13734-41-3

Boc-L-valine

Description:

Boc-L-valine, or tert-butoxycarbonyl-L-valine, is a protected form of the amino acid valine, commonly used in peptide synthesis and organic chemistry. It features a tert-butoxycarbonyl (Boc) group, which serves as a protective group for the amino functionality, allowing for selective reactions without interfering with the amino group. The compound is typically a white to off-white crystalline solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. Boc-L-valine is characterized by its chirality, as it contains a chiral center at the alpha carbon, making it an L-enantiomer. This property is crucial in biological systems and pharmaceutical applications, where the specific stereochemistry can significantly influence activity and efficacy. The compound is stable under standard laboratory conditions but can be hydrolyzed under acidic or basic conditions, releasing the free amino acid valine. Its applications extend to the synthesis of peptides, where the Boc group can be removed under mild acidic conditions, facilitating further reactions.

Formula: C₁₀H₁₉NO₄

InChI: InChI=1S/C10H19NO4/c1-6(2)7(8(12)13)11-9(14)15-10(3,4)5/h6-7H,1-5H3,(H,11,14)(H,12,13)/t7-/m0/s1

InChI key: InChIKey=SZXBQTSZISFIAO-ZETCQYMHSA-N

SMILES: [C@H](NC(OC(C)(C)C)=O)(C(C)C)C(O)=O

Synonyms:

• (2S)-2-(tert-Butoxycarbonylamino)-3-methylbutanoic acid
• (2S)-2-[(tert-butoxycarbonyl)amino]-3-methylbutanoate
• (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-methylbutanoic acid
• (2S)-2-[[(tert-Butoxy)carbonyl]amino]-3-methylbutanoic acid
• (2S)-3-Methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
• (S)-2-(Boc-Amino)-3-Methylbutyric Acid
• (S)-2-(tert-Butoxycarbonylamino)-3-methylbutanoic acid
• (S)-Boc-Valine
• (S)-N-tert-Butoxycarbonylvaline
• <span class="text-smallcaps">L</span>-Valine, N-[(1,1-dimethylethoxy)carbonyl]-
• BOC-valine
• Boc-<span class="text-smallcaps">L</span>-Val
• Boc-<span class="text-smallcaps">L</span>-valine
• Boc-L-Valine
• Boc-Val-OH
• Boc-l-Val-OH
• L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-
• N-(tert-butoxycarbonyl)-D-valine
• N-(tert-butoxycarbonyl)-L-valine
• N-(tert-butoxycarbonyl)valine
• N-BOC-<span class="text-smallcaps">L</span>-valine
• N-BOC-valine
• N-Boc-L-Valine
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-valine
• N-[(1,1-Dimethylethoxy)carbonyl]-L-valine
• N-[(terc-butoxi)carbonil]-L-valina
• N-[(tert-Butoxy)carbonyl]-L-valin
• N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-valine
• N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-valine vinyl ester
• N-tert-Butoxycarbonylvaline
• N-tert-Butyloxycarbonyl-<span class="text-smallcaps">L</span>-valine
• N-tert-Butyloxycarbonyl-L-valine
• N-tert-Butyloxycarbonylvaline
• N-α-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-valine
• N-α-tert-Butoxycarbonyl-L-valine
• Nsc 197197
• Valine, N-carboxy-, N-tert-butyl ester, <span class="text-smallcaps">L</span>-
• Valine, N-carboxy-, N-tert-butyl ester, L-
• t-Butoxycarbonyl-<span class="text-smallcaps">L</span>-valine
• t-Butoxycarbonyl-L-valine
• tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-valine

N-(tert-Butoxycarbonyl)-L-valine

CAS: 13734-41-3

Formula: C₁₀H₁₉NO₄

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 217.27

Ref: 3B-B1333

Boc-Val-OH

CAS: 13734-41-3

M03340 - Boc-Val-OH

Formula: C₁₀H₁₉NO₄

Purity: 98%

Color and Shape: Solid, Powder or Crystalline Powder or Solid

Molecular weight: 217.265

Ref: 10-M03340

N-Boc-L-valine, 98+%

CAS: 13734-41-3

N-Boc-L-valine is used in the multi-peptide synthesis and serves as the amino acid protection monomer. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aes

Formula: C₁₀H₁₉NO₄

Purity: 98+%

Color and Shape: White, Powder

Molecular weight: 217.27

Ref: 02-A16007

Boc-Val-OH

CAS: 13734-41-3

Bachem ID: 4000426.

Formula: C₁₀H₁₉NO₄

Purity: 100.0%

Color and Shape: White

Molecular weight: 217.27

Ref: 01-4000426

N-t-butyloxycarbonyl-N-methyl-L-valine

CAS: 13734-41-3

Formula: C₁₀H₁₉NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 217.2622

Ref: IN-DA0035AR

Boc-Val-OH

CAS: 13734-41-3

Formula: C₁₀H₁₉NO₄

Molecular weight: 217.27

Ref: 7W-GM1187

Nirmatrelvir Impurity 36

CAS: 13734-41-3

Formula: C₁₀H₁₉NO₄

Molecular weight: 217.27

Ref: 4Z-N-148044

N-(tert-Butoxycarbonyl)-L-valine

CAS: 13734-41-3

N-(tert-Butoxycarbonyl)-L-valine

Formula: C₁₀H₁₉NO₄

Purity: 99%

Color and Shape: white to off-white solid

Molecular weight: 217.26g/mol

Ref: 54-OR60097

BOC-L-Valine extrapure, 99%

CAS: 13734-41-3

Formula: C₁₀H₁₉NO₄

Purity: min. 99%

Color and Shape: White to off-white, Crystalline powder

Molecular weight: 217.30

Ref: SR-80577

Boc-L-Valine

Controlled Product

CAS: 13734-41-3

Applications Boc-L-Valine is used in amino acid conjugates as proteasome inhibitors.
References Wan, S. et al.: Int. J. Mol. Med., 26, 447 (2010);

Formula: C₁₀H₁₉NO₄

Color and Shape: Neat

Molecular weight: 217.26

Ref: TR-B673490

Boc-Val-OH

CAS: 13734-41-3

Boc-Val-OH is a natural compound that belongs to the class of ferrocene fatty acid. It has been shown to have antimicrobial properties in cell culture and pharmacokinetic properties in rats. Boc-Val-OH is able to inhibit the activity of serine proteases, which are enzymes that break down proteins and amino acids within cells, as well as cyclopropavir, a virus inhibitor. This compound also has potent inhibitory activity against various microbial strains, including methicillin-resistant Staphylococcus aureus (MRSA) and Helicobacter pylori. Boc-Val-OH has been shown to have hepatoprotective effects in rats with liver damage.

Formula: C₁₀H₁₉NO₄

Purity: Min. 95%

Molecular weight: 217.26 g/mol

Ref: 3D-BLV-2105

Nirmatrelvir Impurity 72

CAS: 13734-41-3

Formula: C₁₀H₁₉NO₄

Molecular weight: 217.27

Ref: ST-EA-CP-N28018

Boc-L-valine

CAS: 13734-41-3

Boc-L-Valine is a model system for the synthesis of peptides. This compound is synthesized in a liquid phase and then purified by column chromatography. It has an antimicrobial activity against Gram-positive bacteria such as Staphylococcus aureus and Escherichia coli, but not against Gram-negative bacteria such as Proteus vulgaris or Pseudomonas aeruginosa. Boc-L-Valine is also used to study the binding of inhibitors and ferrocenes.

Formula: C₁₀H₁₉NO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 217.3 g/mol

Ref: 3D-FB02702