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CAS 137382-38-8

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2-(tert-Butyldimethylsilyl)thiazole

Description:
2-(tert-Butyldimethylsilyl)thiazole is an organosilicon compound characterized by the presence of a thiazole ring, which is a five-membered heterocyclic structure containing both sulfur and nitrogen atoms. The tert-butyldimethylsilyl group serves as a protective or modifying group, enhancing the compound's stability and solubility in organic solvents. This compound typically exhibits properties such as moderate polarity due to the thiazole moiety, while the silyl group contributes to its hydrophobic characteristics. It is often utilized in organic synthesis, particularly in the field of medicinal chemistry, where it can serve as an intermediate or a building block for more complex molecules. The presence of the silyl group can also facilitate reactions such as deprotection or coupling reactions. Additionally, 2-(tert-Butyldimethylsilyl)thiazole may exhibit specific reactivity patterns due to the electron-withdrawing nature of the thiazole ring, making it a valuable compound in various synthetic applications. Safety data should be consulted for handling and storage, as with any chemical substance.
Formula:C9H17NSSi
InChI:InChI=1/C9H17NSSi/c1-9(2,3)12(4,5)8-10-6-7-11-8/h6-7H,1-5H3
SMILES:CC(C)(C)[Si](C)(C)c1nccs1
Synonyms:
  • 2-[tert-Butyl(dimethyl)silyl]-1,3-thiazole
  • Thiazole, 2-[(1,1-dimethylethyl)dimethylsilyl]-
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