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CAS 137403-12-4

:

L-694,247

Description:
L-694,247 is a synthetic compound that belongs to the class of non-peptide small molecules. It is primarily recognized for its role as a selective antagonist of the neuropeptide Y (NPY) Y1 receptor, which is implicated in various physiological processes, including appetite regulation, anxiety, and cardiovascular function. The compound has been studied for its potential therapeutic applications in conditions such as obesity and anxiety disorders. L-694,247 exhibits high affinity and selectivity for the Y1 receptor, making it a valuable tool in pharmacological research. Its chemical structure features a distinct arrangement of functional groups that contribute to its biological activity. As with many research compounds, safety and handling precautions are essential, as the full spectrum of its pharmacological effects and potential side effects are still under investigation. Overall, L-694,247 serves as an important compound in the exploration of neuropeptide signaling pathways and their implications in health and disease.
Formula:C20H21N5O3S
InChI:InChI=1/C20H21N5O3S/c1-29(26,27)25-16-5-2-13(3-6-16)10-19-23-20(28-24-19)14-4-7-18-17(11-14)15(8-9-21)12-22-18/h2-7,11-12,22,25H,8-10,21H2,1H3
InChI key:InChIKey=HKXMQLISPYELRD-UHFFFAOYSA-N
SMILES:C(CN)C=1C=2C(=CC=C(C2)C3=NC(CC4=CC=C(NS(C)(=O)=O)C=C4)=NO3)NC1
Synonyms:
  • 2-[5-[3-(4-Methylsulfonylamino)Benzyl-1,2,4-Oxadiazol-5-Yl]-1H-Indol-3-Yl]Ethanamine
  • 2-[5-[3-(4-Methylsulphonylamino)Benzyl-1,2,4-Oxadiazol-5-Yl]-1H-Indol-3-Yl] Ethanamine
  • Methanesulfonamide, N-[4-[[5-[3-(2-aminoethyl)-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]phenyl]-
  • N-[4-[[5-[3-(2-Aminoethyl)-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]phenyl]-methanesulfonamide
  • L 694247
  • 3-benzyl-5-(1H-indol-3-yl)-1,2,4-oxadiazole
  • L-694
  • L694
  • L 694
  • N-(4-((5-(3-(2-Aminoethyl)-1H-indol-5-yl)-1,2,4-oxadiazol-3-yl)methyl)phenyl)methanesulfonamid
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Found 4 products.