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(S)-Hydroxychloroquine

CAS 137433-24-0: (S)-Hydroxychloroquine

Description:(S)-Hydroxychloroquine is a chiral compound primarily known for its use as an antimalarial and immunomodulatory agent. It is a derivative of chloroquine, featuring a hydroxyl group that enhances its solubility and bioavailability. The substance exhibits a molecular formula that includes carbon, hydrogen, nitrogen, and oxygen, reflecting its complex structure. As a racemic mixture, hydroxychloroquine exists in two enantiomeric forms, with the (S)-enantiomer being the more therapeutically active form. It functions by interfering with the lysosomal activity in cells, which is crucial for the replication of certain viruses and the modulation of immune responses. The compound is commonly used in the treatment of autoimmune diseases such as rheumatoid arthritis and lupus erythematosus, in addition to its role in malaria prophylaxis. Its safety profile includes potential side effects, such as gastrointestinal disturbances and retinal toxicity with long-term use. Overall, (S)-Hydroxychloroquine is a significant pharmaceutical agent with diverse applications in both infectious and autoimmune diseases.

Formula:C18H26ClN3O

InChI:InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/t14-/m0/s1

InChI key:InChIKey=XXSMGPRMXLTPCZ-AWEZNQCLSA-N

SMILES:ClC=1C=CC=2C(=NC=CC2NC(C)CCCN(CC)CCO)C1

  • Synonyms:
  • 2-[[(4S)-4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol
  • (S)-Hydroxychloroquine
  • Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, (S)-
  • Ethanol, 2-[[(4S)-4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-
  • Hydroxychloroquine
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(S)-Hydroxychloroquine

Controlled Product
CAS:137433-24-0

Ref: TR-C373715

25mg391.00 €
100mg1,514.00 €
Estimated delivery in United States, on Tuesday 18 Mar 2025
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(S)-(+)-Hydroxy Chloroquine-d4 Diphosphate

Controlled Product

Ref: TR-H905307

25mg21,891.00 €
Estimated delivery in United States, on Wednesday 16 Apr 2025
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(S)-(+)-Hydroxy Chloroquine-d5 Diphosphate

Controlled Product
CAS:137433-24-0158749-76-9

Ref: TR-H905308

25mg16,483.00 €
Estimated delivery in United States, on Wednesday 16 Apr 2025
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(S)-Hydroxychloroquine

CAS:137433-24-0

Ref: TM-T12799

25mg1,444.00 €
50mg1,882.00 €
100mg2,375.00 €
Estimated delivery in United States, on Thursday 24 Apr 2025
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(S)-Hydroxychloroquine

CAS:137433-24-0

Ref: 3D-MFA43324

1mgDiscontinuedRequest information
5mgDiscontinuedRequest information
10mgDiscontinuedRequest information
25mgDiscontinuedRequest information
50mgDiscontinuedRequest information
250mgDiscontinuedRequest information
Discontinued product
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