CAS 137433-24-0: (S)-Hydroxychloroquine
Description:(S)-Hydroxychloroquine is a chiral compound primarily known for its use as an antimalarial and immunomodulatory agent. It is a derivative of chloroquine, featuring a hydroxyl group that enhances its solubility and bioavailability. The substance exhibits a molecular formula that includes carbon, hydrogen, nitrogen, and oxygen, reflecting its complex structure. As a racemic mixture, hydroxychloroquine exists in two enantiomeric forms, with the (S)-enantiomer being the more therapeutically active form. It functions by interfering with the lysosomal activity in cells, which is crucial for the replication of certain viruses and the modulation of immune responses. The compound is commonly used in the treatment of autoimmune diseases such as rheumatoid arthritis and lupus erythematosus, in addition to its role in malaria prophylaxis. Its safety profile includes potential side effects, such as gastrointestinal disturbances and retinal toxicity with long-term use. Overall, (S)-Hydroxychloroquine is a significant pharmaceutical agent with diverse applications in both infectious and autoimmune diseases.
Formula:C18H26ClN3O
InChI:InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/t14-/m0/s1
InChI key:InChIKey=XXSMGPRMXLTPCZ-AWEZNQCLSA-N
SMILES:ClC=1C=CC=2C(=NC=CC2NC(C)CCCN(CC)CCO)C1
- Synonyms:
- 2-[[(4S)-4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol
- (S)-Hydroxychloroquine
- Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, (S)-
- Ethanol, 2-[[(4S)-4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-
- Hydroxychloroquine
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(S)-Hydroxychloroquine
Controlled ProductRef: TR-C373715
25mg | 391.00 € | ||
100mg | 1,514.00 € |
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(S)-(+)-Hydroxy Chloroquine-d4 Diphosphate
Controlled ProductRef: TR-H905307
25mg | 21,891.00 € |
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(S)-(+)-Hydroxy Chloroquine-d5 Diphosphate
Controlled ProductRef: TR-H905308
25mg | 16,483.00 € |
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(S)-Hydroxychloroquine
Ref: TM-T12799
25mg | 1,444.00 € | ||
50mg | 1,882.00 € | ||
100mg | 2,375.00 € |
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(S)-Hydroxychloroquine
Ref: 3D-MFA43324
1mg | Discontinued | Request information | |
5mg | Discontinued | Request information | |
10mg | Discontinued | Request information | |
25mg | Discontinued | Request information | |
50mg | Discontinued | Request information | |
250mg | Discontinued | Request information |