CAS 1374639-79-8

Ribociclib succinate hydrate

CAS: 1374639-79-8

Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively).

Formula: C₂₇H₃₈N₈O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 570.651

Ref: TM-T15731

Ribociclib succinate hydrate

CAS: 1374639-79-8

Ribociclib succinate hydrate is a selective cyclin-dependent kinase (CDK) inhibitor, which is synthesized through chemical processes. Its primary mode of action involves the selective inhibition of CDK4 and CDK6, pivotal proteins in regulating the cell cycle. By hindering the phosphorylation of the retinoblastoma protein (Rb), Ribociclib effectively causes cell cycle arrest at the G1 phase, thereby preventing cancer cell proliferation.

Formula: C₂₇H₃₈N₈O₆

Purity: Min. 95%

Molecular weight: 570.6 g/mol

Ref: 3D-ZEC63979