CAS 1374647-94-5

DC4 Crosslinker

CAS: 1374647-94-5

DC4 crosslinker, an 18Å mass spectrometry-cleavable crosslinking reagent, features two intrinsic positive charges facilitating the fragmentation of cross-linked peptides into their constituent peptides through collision-induced dissociation or in-source decay. Initial fragmentation leads to cleavage adjacent to the positive charges, enabling the identification of cross-linked peptides as pairs of ions with precise mass separation. Furthermore, the resultant intact peptide fragments can undergo further fragmentation, producing a sequence of b- and y-ions for peptide identification.

Formula: C₂₂H₃₂Br₂N₄O₈

Color and Shape: Solid

Molecular weight: 640.326

Ref: TM-T84457

(2,5-Dioxopyrrolidin-1-yl) 4-[4-[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutyl]-1,4-diazoniabicyclo[2.2.2]octan-1-yl]butanoate, dibromi de

CAS: 1374647-94-5

(2,5-Dioxopyrrolidin-1-yl) 4-[4-[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutyl]-1,4-diazoniabicyclo[2.2.2]octan-1-yl]butanoate, dibromide is a chemical compound that functions as a bifunctional cross-linking agent. It is synthesized through the reaction of specific amine and carboxylic acid compounds under controlled conditions. The compound features N-hydroxysuccinimide esters and quaternary diazabicyclooctane groups, enhancing its reactivity and solubility.

Formula: C₂₂H₃₂Br₂N₄O₈

Purity: Min. 95%

Molecular weight: 640.3 g/mol

Ref: 3D-ZEC64794