CAS 13754-56-8

Dioxopromethazine

Description:

Dioxopromethazine, identified by its CAS number 13754-56-8, is a chemical compound that belongs to the phenothiazine class of medications. It is primarily known for its antihistaminic properties, which make it useful in treating allergic reactions and symptoms associated with motion sickness. The compound features a complex structure that includes a phenothiazine backbone, which is characterized by a sulfur atom and nitrogen atoms within a three-ring system. Dioxopromethazine exhibits sedative effects, making it beneficial for managing anxiety and sleep disorders. Its pharmacological profile includes antagonistic activity at histamine H1 receptors, contributing to its effectiveness in alleviating allergic symptoms. Additionally, it may have anticholinergic properties, which can lead to side effects such as dry mouth and drowsiness. As with many medications, the use of dioxopromethazine should be monitored for potential interactions with other drugs and contraindications, particularly in individuals with certain medical conditions. Overall, it is a versatile compound with significant therapeutic applications in clinical settings.

Formula: C₁₇H₂₀N₂O₂S

InChI: InChI=1S/C17H20N2O2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)22(20,21)17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3

InChI key: InChIKey=FDXKCOBAFGSMDJ-UHFFFAOYSA-N

SMILES: C(C(N(C)C)C)N1C=2C(S(=O)(=O)C=3C1=CC=CC3)=CC=CC2

Synonyms:

• 1-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N-dimethylpropan-2-amine
• 1-(5,5-Dioxophenothiazin-10-yl)-N,N-dimethylpropan-2-amine
• 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, 5,5-dioxide (9CI)
• 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, 5,5-dioxide
• 10H-phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, 5,5-dioxide
• 9,9-Dioxopromethazine
• 9,9-Dioxypromethazin
• Dioxopromethazine
• Phenothiazine, 10-[2-(dimethylamino)propyl]-, 5,5-dioxide
• Promethazine 5,5-dioxide
• Prothanon

DioxopromethaxineHydrochloride

CAS: 13754-56-8

Formula: C₁₇H₂₀N₂O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 316.4179

Ref: IN-DA0013JB

Dioxopromethazine

CAS: 13754-56-8

Dioxopromethazine (Dioxoprothazine) is a drug for the treatment of a cough and expectoration. It also can be used in local anesthesia.

Formula: C₁₇H₂₀N₂O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 316.42

Ref: TM-T3609

Promethazine Sulfone

CAS: 13754-56-8

Applications Promethazine Sulfone, is a metabolite of Promethazine (P757000), which is a drug from antihistamine family. It has strong sedative effects and in some countries used for the treatment of insomnia. It has also antiemetic and anticholinergic properties.
References Edge, W., et al.: J. Pharm. Pharmacol., 5, 279 (1953), Huang, et al.: J. Pharm. Sci., 59, 772 (1970), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 5, 429 (1976)

Formula: C₁₇H₂₀N₂O₂S

Color and Shape: Neat

Molecular weight: 316.42

Ref: TR-P757015