CAS 137563-63-4

eurystatin A

Description:

Eurystatin A is a natural product belonging to the class of polyketides, specifically known for its antibiotic properties. It is produced by certain strains of the bacterium *Streptomyces* and exhibits significant biological activity, particularly against various strains of bacteria and fungi. The compound is characterized by its complex molecular structure, which includes multiple functional groups that contribute to its bioactivity. Eurystatin A has been studied for its potential applications in medicine, particularly in the development of new antimicrobial agents. Its mechanism of action typically involves interference with cellular processes in target organisms, leading to growth inhibition or cell death. Additionally, eurystatin A may exhibit cytotoxic effects, making it a subject of interest in cancer research. As with many natural products, the extraction and purification of eurystatin A can be challenging, and ongoing research aims to explore its full therapeutic potential and to understand its structure-activity relationships.

Formula: C₂₃H₃₈N₄O₅

InChI: InChI=1/C23H38N4O5/c1-14(2)9-6-7-11-19(28)26-17-10-8-12-24-21(30)18(13-15(3)4)27-23(32)20(29)16(5)25-22(17)31/h7,11,14-18H,6,8-10,12-13H2,1-5H3,(H,24,30)(H,25,31)(H,26,28)(H,27,32)/b11-7+/t16-,17-,18-/m0/s1

Synonyms:

• eurystatin A
• L-Leucine, N2-[(2E)-6-methyl-1-oxo-2-hepten-1-yl]-L-ornithyl-(3S)-3-amino-2-oxobutanoyl-, (3→1)-lactam
• 2-Heptenamide, 6-methyl-N-(7-methyl-3-(2-methylpropyl)-2,5,6,9-tetraoxo-1,4,8-triazacyclotridec-10-yl)-, (3S-(3R*,7R*,10R*(E)))-
• (2E)-6-methyl-N-[(3S,7S,10S)-7-methyl-3-(2-methylpropyl)-2,5,6,9-tetraoxo-1,4,8-triazacyclotridecan-10-yl]hept-2-enamide
• BU 4164E-A

Eurystatin A

CAS: 137563-63-4

Eurystatin A is a prolyl endopeptidase inhibitor, with L-leucine and L-ornithine serving as direct precursors to the L-leucine and L-ornithine components of eurystatins A.

Formula: C₂₃H₃₈N₄O₅

Color and Shape: Solid

Molecular weight: 450.572

Ref: TM-TN10435