CAS 137813-36-6
:Cyclo(-Arg-Ala-Asp-D-Phe-Val)
Description:
Cyclo(-Arg-Ala-Asp-D-Phe-Val) is a cyclic peptide that consists of five amino acids: arginine (Arg), alanine (Ala), aspartic acid (Asp), D-phenylalanine (D-Phe), and valine (Val). Its cyclic structure enhances its stability and bioactivity compared to linear peptides, making it of interest in various biochemical applications. The presence of D-phenylalanine, a non-natural amino acid, contributes to its resistance to enzymatic degradation, which is advantageous for therapeutic uses. This peptide exhibits properties such as potential binding affinity to specific receptors, which can be leveraged in drug design, particularly in targeting certain biological pathways or diseases. Additionally, the arrangement of amino acids in the cyclic structure can influence its conformation and interaction with biological molecules, making it a subject of study in fields like medicinal chemistry and pharmacology. Overall, Cyclo(-Arg-Ala-Asp-D-Phe-Val) represents a versatile compound with implications in peptide-based therapeutics and research.
Formula:C27H40N8O7
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Found 2 products.
Cyclo(Arg-Ala-Asp-D-Phe-Val)
CAS:<p>Cyclo(Arg-Ala-Asp-D-Phe-Val) is an active, cyclic peptide that has been shown to have localized effects on the metaphase, meiosis, and gamete cells. Cyclo(Arg-Ala-Asp-D-Phe-Val) is a cilengitide, which are small molecules that bind to calcium ions and increase intracellular levels of calcium. This leads to the activation of biochemical pathways in cells. Cyclo(Arg-Ala-Asp-D-Phe-Val) has been shown to have a diacylglycerol antagonist effect in porcine oocytes and was used in clinical trials for the treatment of infertility. Cyclo(Arg-Ala-Asp-D-Phe Val) also has apoptotic activity in cancer cells.</p>Formula:C27H40N8O7Purity:Min. 95%Molecular weight:588.68 g/molCyclo(-Arg-Ala-Asp-D-Phe-Val)
CAS:<p>Cyclo(-Arg-Ala-Asp-D-Phe-Val) is a cyclic peptide that binds to the extracellular domain of the receptor, activating it. It is a protein kinase C activator that has been shown to increase proliferation and survival in vitro studies. Cyclo(-Arg-Ala-Asp-D-Phe-Val) has also been shown to have antiangiogenic effects in vivo and to inhibit the growth of cancer cells. This peptide has not yet been tested for toxicity or carcinogenicity in humans, but preliminary studies on rats show no significant toxic effects.</p>Formula:C27H40N8O7Purity:Min. 95%Molecular weight:588.66 g/mol
