CAS 137862-53-4: Valsartan

Description: Valsartan is an angiotensin II receptor blocker (ARB) primarily used in the treatment of hypertension and heart failure. It functions by inhibiting the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby promoting vasodilation and lowering blood pressure. Valsartan is characterized by its chemical formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms, reflecting its complex structure. The substance is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Valsartan is generally well-tolerated, but like all medications, it may have side effects, including dizziness, fatigue, and potential renal impairment. It is contraindicated in certain populations, such as pregnant women, due to risks of fetal harm. The compound is also subject to various drug interactions, necessitating careful management in patients taking multiple medications. Overall, Valsartan plays a significant role in cardiovascular therapy, contributing to improved patient outcomes in managing high blood pressure and heart-related conditions.

Formula: C₂₄H₂₉N₅O₃

InChI: InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1

InChI key: InChIKey=ACWBQPMHZXGDFX-QFIPXVFZSA-N

SMILES: O=C(O)C(N(C(=O)CCCC)CC=1C=CC(=CC1)C=2C=CC=CC2C3=NN=NN3)C(C)C

Synonyms:

• N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
• N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}valine
• CGP 48933
• 3-methyl-2-[pentanoyl-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid
• L-Valine, N-(1-oxopentyl)-N-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
• Valsartan
• Valsartan(Diovan)
• D-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-D-valine
• L-Valine, N-(1-oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
• N-(1-Oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine
• n-(1-oxopentyl)-n-((2'-(1h-tetrazol-5-yl)(1,1'-biphenyl)-3-yl)methyl)-l-valine

Valsartan

CAS: 137862-53-4

• Formula: C₂₄H₂₉N₅O₃
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 435.53

Valsartan

CAS: 137862-53-4

• Formula: C₂₄H₂₉N₅O₃
• Purity: 98.3%
• Color and Shape: Off White Solid
• Molecular weight: 435.22704

Valsartan for system suitability CRS

CAS: 137862-53-4

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: Powder
• Molecular weight: 435.5188

Valsartan for peak identification CRS

CAS: 137862-53-4

Valsartan CRS

CAS: 137862-53-4

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: Powder
• Molecular weight: 435.5188

Valsartan

CAS: 137862-53-4

Cardiovascular drugs, nesoi

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: White Powder
• Molecular weight: 435.22704

L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-

CAS: 137862-53-4

• Formula: C₂₄H₂₉N₅O₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 435.5188

Valsartan, USP grade

CAS: 137862-53-4

• Formula: C₂₄H₂₉N₅O₃
• Purity: ≤ 0.1%
• Color and Shape: White to off-white or beige powder
• Molecular weight: 435.52

Valsartan

CAS: 137862-53-4

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 435.53

Valsartan

CAS: 137862-53-4

• Formula: C₂₄H₂₉N₅O₃
• Purity: ≥ 98.0% (dried basis)
• Color and Shape: White to off-white or beige powder
• Molecular weight: 435.52

(S)-2-(N-((2?-(1H-Tetrazol-5-yl)-[1,1?-Biphenyl]-4-yl)Methyl)Pentanamido)-3-Methylbutanoic Acid

CAS: 137862-53-4

• Purity: 98%
• Molecular weight: 435.52g/mol

Valsartan

CAS: 137862-53-4

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: White to almost white to light beige, Powder
• Molecular weight: 435.53

Valsartan

CAS: 137862-53-4

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: Neat
• Molecular weight: 435.52

Valsartan

CAS: 137862-53-4

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: Neat
• Molecular weight: 435.52

Valsartan

CAS: 137862-53-4

Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that …

• Formula: C₂₄H₂₉N₅O₃
• Purity: 99.24% - 99.76%
• Color and Shape: White Solid Powder
• Molecular weight: 435.52

Valsartan RS

CAS: 137862-53-4

• Color and Shape: White Solid Powder

Valsartan

CAS: 137862-53-4

Stability Hygroscopic Applications A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive. References Criscione, L., et al.: …

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: White To Off-White
• Molecular weight: 435.52

(2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}pentanamido)butanoic acid

CAS: 137862-53-4

• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 435.52801513671875

N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine

CAS: 137862-53-4

• Purity: 97.0%
• Color and Shape: Solid, Powder
• Molecular weight: 435.52801513671875

Valsartan - Bio-X ™

CAS: 137862-53-4

Valsartan is an angiotensin receptor blocker that is used to treat hypertension and in combination …

• Formula: C₂₄H₂₉N₅O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 435.52 g/mol

Valsartan

CAS: 137862-53-4

AT1 receptor antagonist

• Formula: C₂₄H₂₉N₅O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 435.52 g/mol

Nitroso Valsartan Methyl Ester

CAS: 137862-53-4

Applications Nitroso Valsartan Methyl Ester is an impurity of Valsartan (V095750) a nonpeptide angiotensin II …

• Formula: C₂₀H₂₂N₆O₃
• Color and Shape: Neat
• Molecular weight: 394.427

Nitroso (S)-Valsartan (N1, N2 Mixture)

CAS: 137862-53-4

• Formula: C₂₄H₂₈N₆O₄
• Color and Shape: Neat
• Molecular weight: 929.034