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CAS 137862-53-4

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Valsartan

Description:
Valsartan is an angiotensin II receptor blocker (ARB) primarily used in the treatment of hypertension and heart failure. It functions by inhibiting the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby promoting vasodilation and lowering blood pressure. Valsartan is characterized by its chemical formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms, reflecting its complex structure. The substance is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Valsartan is generally well-tolerated, but like all medications, it may have side effects, including dizziness, fatigue, and potential renal impairment. It is contraindicated in certain populations, such as pregnant women, due to risks of fetal harm. The compound is also subject to various drug interactions, necessitating careful management in patients taking multiple medications. Overall, Valsartan plays a significant role in cardiovascular therapy, contributing to improved patient outcomes in managing high blood pressure and heart-related conditions.
Formula:C24H29N5O3
InChI:InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
InChI key:InChIKey=ACWBQPMHZXGDFX-QFIPXVFZSA-N
SMILES:C(N([C@@H]([C@H](C)C)C(O)=O)C(CCCC)=O)C1=CC=C(C2=C(C=CC=C2)C=3NN=NN3)C=C1
Synonyms:
  • N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
  • N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}valine
  • CGP 48933
  • 3-methyl-2-[pentanoyl-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid
  • L-Valine, N-(1-oxopentyl)-N-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
  • Valsartan
  • Valsartan(Diovan)
  • D-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
  • N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-D-valine
  • L-Valine, N-(1-oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
  • See more synonyms
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products per page.Found 23 products.
  • Valsartan - Bio-X ™
    Biosynth
    + Info

    Valsartan - Bio-X ™

    CAS:
    <p>Valsartan is an angiotensin receptor blocker that is used to treat hypertension and in combination with other antihypertensive agents. This drug works by binding to the angiotensin receptor 1 (AT1) and preventing angiotensin II from binding and exerting its hypertensive effects. This leads to a reduction in blood pressure and reduced cardiac activity.</p>
    Formula:C24H29N5O3
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:435.52 g/mol

    Ref: 3D-BV164506

    50mg
    135.00€
  • Valsartan
    Biosynth
    + Info

    Valsartan

    CAS:
    <p>AT1 receptor antagonist</p>
    Formula:C24H29N5O3
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:435.52 g/mol

    Ref: 3D-FV28662

    10g
    203.00€
    25g
    325.00€
    50g
    477.00€
    100g
    509.00€
    250g
    725.00€
  • Nitroso Valsartan Methyl Ester
    TRC
    + Info

    Nitroso Valsartan Methyl Ester

    Controlled Product
    CAS:
    <p>Applications Nitroso Valsartan Methyl Ester is an impurity of Valsartan (V095750) a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>
    Formula:C20H22N6O3
    Color and Shape:Neat
    Molecular weight:394.427

    Ref: TR-N002960

    100mg
    1,022.00€