CAS 137862-87-4: Valsartan

Description: Valsartan is an angiotensin II receptor blocker (ARB) primarily used in the treatment of hypertension and heart failure. Its chemical formula is C24H29N5O3, and it features a biphenyl structure with a tetrazole ring, which contributes to its pharmacological activity. Valsartan works by inhibiting the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby promoting vasodilation and reducing blood pressure. The substance is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Valsartan is generally well-tolerated, but like all medications, it may have side effects, including dizziness, fatigue, and potential renal impairment. It is contraindicated in certain populations, such as pregnant women, due to the risk of fetal harm. The compound is also subject to various regulatory standards to ensure its safety and efficacy in clinical use.

Formula: C₂₄H₂₉N₅O₃

InChI: InChI=1/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m1/s1

Synonyms:

• 3-Methyl-2-[Pentanoyl-[[4-[2-(2H-Tetrazol-5-Yl)Phenyl]Phenyl]Methyl]Amino]-Butanoic Acid
• N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}valine
• N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
• N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-D-valine
• D-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• Valsartan(Diovan)
• N-(1-Oxopentyl)-N-((2'-(1H-Tetrazol-5-Yl)(1,1'-Biphenyl)-3-Yl)Methyl)-L-Valine

Valsartan Related Compound A (N-Valeryl-N-{[2'-(1H-tetrazole-5-yl)biphenyl-4-yl]methyl}D-valine)

CAS: 137862-87-4

Aromatic or modified aromatic heterocyclic compounds withnitrogen hetero-atom(s) only nesoi

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: Off-White Powder
• Molecular weight: 435.22704

D-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-

CAS: 137862-87-4

• Formula: C₂₄H₂₉N₅O₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 435.5188

Valsartan EP Impurity A (Valsartan USP Related Compound A, ent-Valsartan)

CAS: 137862-87-4

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 435.53

(2R)-3-Methyl-2-[pentanoyl[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]butanoic Acid (Valsartan (R)-Enantiomer)

CAS: 137862-87-4

• Color and Shape: Neat

ent-Valsartan

CAS: 137862-87-4

Impurity Valsartan USP Related Compound A Applications ent-Valsartan (Valsartan USP Related Compound A) is the …

• Formula: C₂₄H₂₉N₅O₃
• Color and Shape: Neat
• Molecular weight: 435.52

(R)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid

CAS: 137862-87-4

• Purity: 95.0%
• Molecular weight: 435.52801513671875

Valsartan EP Impurity A

CAS: 137862-87-4

• Formula: C₂₄H₂₉N₅O₃
• Molecular weight: 435.52

N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-D-valine

CAS: 137862-87-4

N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-D-valine is a potent and selective inhibitor of the enzyme lipase. It prevents the hydrolysis …

• Formula: C₂₄H₂₉N₅O₃
• Purity: Min. 95%
• Color and Shape: White To Off-White Solid
• Molecular weight: 435.52 g/mol