CAS 1379686-29-9

3-[[[(4-Chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-N-pentyl-1-pyrrolidinecarboxamide

Description:

The chemical substance known as 3-[[[(4-Chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-N-pentyl-1-pyrrolidinecarboxamide, with the CAS number 1379686-29-9, is a synthetic compound characterized by its complex molecular structure, which includes a pyrrolidine ring, a carboxamide functional group, and multiple aromatic and heterocyclic components. The presence of a 4-chlorophenyl group and a 5-nitro-2-thienyl moiety suggests potential biological activity, possibly influencing its pharmacological properties. The pentyl chain contributes to its lipophilicity, which may affect its solubility and permeability in biological systems. This compound is likely to exhibit specific interactions with biological targets, making it of interest in medicinal chemistry and drug development. Its unique combination of functional groups may also impart distinctive chemical reactivity and stability characteristics. However, detailed studies would be necessary to fully elucidate its properties, including its synthesis, mechanism of action, and potential applications in therapeutic contexts.

Formula: C₂₃H₃₁ClN₄O₃S

InChI: InChI=1S/C23H31ClN4O3S/c1-2-3-4-12-25-23(29)27-13-11-19(16-27)15-26(14-18-5-7-20(24)8-6-18)17-21-9-10-22(32-21)28(30)31/h5-10,19H,2-4,11-17H2,1H3,(H,25,29)

InChI key: InChIKey=PPUYOYQTTWJTIU-UHFFFAOYSA-N

SMILES: N(CC1CN(C(NCCCCC)=O)CC1)(CC=2SC(N(=O)=O)=CC2)CC3=CC=C(Cl)C=C3

Synonyms:

• 3-[[(4-Chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide
• 3-[[[(4-Chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-N-pentyl-1-pyrrolidinecarboxamide
• 1-Pyrrolidinecarboxamide, 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-N-pentyl-
• SR 9011

SR9011

CAS: 1379686-29-9

SR9011

Purity: ≥98%

Molecular weight: 479.04g/mol

Ref: 54-BUP01929

SR9011

CAS: 1379686-29-9

SR9011 is a REV-ERB agonist (IC50: 790 nM, REV-ERBα; IC50: 560 nM, REV-ERBβ).

Formula: C₂₃H₃₁ClN₄O₃S

Purity: 99.64% - 99.65%

Color and Shape: Solid

Molecular weight: 479.04

Ref: TM-T3688

SR 9011

CAS: 1379686-29-9

Applications SR 9011 is a synthetic REV-ERBα/β agonist with activity in vivo. It is a lead compound for a new class of cancer drugs associated with the body’s circadian clock.
References Solt, L.A., et. al.: Nature, 485, 7396 (2012); Chem. and Eng. News. p.8, Jan. 15, 2018

Formula: C₂₃H₃₁ClN₄O₃S

Color and Shape: Neat

Molecular weight: 479.00

Ref: TR-S684260

SR9011

Controlled Product

CAS: 1379686-29-9

SR9011 is a small-molecule drug that has been shown to have anti-cancer effects. It is currently undergoing clinical trials for the treatment of cancer, including glioblastoma (brain cancer) and non-small cell lung cancer. SR9011 inhibits the activation of microglia cells in the brain, which are associated with neurological disorders such as Alzheimer's disease and Parkinson's disease. This drug also reduces skin inflammation and can be used to treat inflammatory diseases such as Crohn's disease or ulcerative colitis. SR9011 can also be used to treat metabolic disorders, such as type 2 diabetes or obesity. The mechanism of action for SR9011 is not fully understood, but it has been shown to activate autophagy in human liver cells and beta-cells in the pancreas.
SR9011 was originally developed by Sirtris Pharmaceuticals under the code name "SR9009."

Formula: C₂₃H₃₁ClN₄O₃S

Purity: Min. 95%

Molecular weight: 479.04 g/mol

Ref: 3D-EFC68629

SR9011

CAS: 1379686-29-9

Formula: C₂₃H₃₁ClN₄O₃S

Purity: 99%

Color and Shape: Solid

Molecular weight: 479.0352

Ref: IN-DA009CKB