CAS 1379686-30-2

SR 9009

Description:

SR 9009, also known as Stenabolic, is a synthetic compound that belongs to a class of drugs known as Rev-Erb agonists. It is primarily researched for its potential effects on metabolism and exercise performance. SR 9009 is characterized by its ability to enhance mitochondrial function, increase endurance, and promote fat loss by modulating the circadian rhythm and influencing the expression of genes involved in metabolism. The compound interacts with the Rev-Erb protein, which plays a crucial role in regulating various metabolic processes, including lipid and glucose metabolism. Although SR 9009 has shown promise in preclinical studies, it is important to note that it is not approved for human use and remains a subject of ongoing research. Its safety profile, long-term effects, and potential therapeutic applications are still being investigated. As with any substance, caution is advised, and it is essential to rely on scientific evidence and regulatory guidelines when considering its use.

Formula: C₂₀H₂₄ClN₃O₄S

InChI: InChI=1S/C20H24ClN3O4S/c1-2-28-20(25)23-10-9-16(13-23)12-22(11-15-3-5-17(21)6-4-15)14-18-7-8-19(29-18)24(26)27/h3-8,16H,2,9-14H2,1H3

InChI key: InChIKey=MMJJNHOIVCGAAP-UHFFFAOYSA-N

SMILES: N(CC1CN(C(OCC)=O)CC1)(CC=2SC(N(=O)=O)=CC2)CC3=CC=C(Cl)C=C3

Synonyms:

• 1-Pyrrolidinecarboxylic acid, 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-, ethyl ester
• Ethyl 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylate
• SR 9009
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• Stenabolic (SR9009)
• 3-[[[(4-Chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylic acid ethyl ester
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• REV-ERB Agonist II
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• SR9009 USP/EP/BP
• ethyl 3-({[(4-chlorophenyl)methyl][(5-nitrothiophen-2-yl)methyl]amino}methyl)pyrrolidine-1-carboxylate
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• ethyl-3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)pyrrolidine-1-carboxylate
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• STENABOLIC
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SR9009

CAS: 1379686-30-2

SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.

Formula: C₂₀H₂₄ClN₃O₄S

Purity: 99.94% - >99.99%

Color and Shape: Solid

Molecular weight: 437.94

Ref: TM-T3685

SR 9009

CAS: 1379686-30-2

Applications SR 9009 is a synthetic REV-ERB agonist that regulates circadian behavior and metabolism; has potential use in the treatment of sleep disorders and metabolic diseases. It is a lead compound for a new class of cancer drugs associated with the body’s circadian clock.
References Solt, L.A., et. al.: Nature, 485, 62 (2012); Chem. and Eng. News. p.8, Jan. 15, 2018

Formula: C₂₀H₂₄ClN₃O₄S

Color and Shape: White To Beige

Molecular weight: 437.90

Ref: TR-S684255

SR9009

Controlled Product

CAS: 1379686-30-2

SR9009 is a synthetic, nonsteroidal compound that is a modulator of Toll-like receptor (TLR) signaling pathways. The TLR pathway is involved in the recognition of microbial pathogens and initiates an inflammatory response to these infections. SR9009 inhibits the LPS-induced inflammatory response by suppressing TLR signaling. This drug also has activity against metabolic disorders such as atherosclerosis and liver steatosis, as well as infectious diseases such as HIV and influenza virus. SR9009 may also be useful for treating viral life cycle and autophagy.

Formula: C₂₀H₂₄ClN₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 437.94 g/mol

Ref: 3D-FS159307

SR9009

CAS: 1379686-30-2

Formula: C₂₀H₂₄ClN₃O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 437.9403

Ref: IN-DA009BPI