CAS 1380392-05-1

Pyrrolo[1,2-a]quinoxalin-4(5H)-one,5-[3-[4-(4-chlorophenyl)-1-piperidinyl]propyl]-

Description:

Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 5-[3-[4-(4-chlorophenyl)-1-piperidinyl]propyl]- is a complex organic compound characterized by its unique bicyclic structure, which includes a pyrroloquinoxaline core. This compound features a piperidine moiety substituted with a propyl chain and a para-chlorophenyl group, contributing to its potential biological activity. The presence of the chlorophenyl group may enhance lipophilicity, influencing its interaction with biological targets. Typically, compounds of this nature are investigated for their pharmacological properties, including potential applications in neuroscience or as therapeutic agents. The molecular structure suggests the possibility of engaging in various chemical interactions, such as hydrogen bonding and π-π stacking, which are crucial for biological activity. Additionally, the compound's synthesis and stability can be influenced by the functional groups present, making it a subject of interest in medicinal chemistry and drug development. Overall, this compound exemplifies the intricate relationship between molecular structure and biological function, warranting further exploration in research settings.

Formula: C₂₅H₂₆ClN₃O

Synonyms:

• Pyrrolo[1,2-a]quinoxalin-4(5H)-one,5-[3-[4-(4-chlorophenyl)-1-piperidinyl]propyl]-
• 5-(3-(4-(4-chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one

5-(3-(4-(4-Chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one

CAS: 1380392-05-1

Formula: C₂₅H₂₆ClN₃O

Purity: 97%

Color and Shape: Solid

Molecular weight: 419.9464

Ref: IN-DA01KYPN

5-(3-(4-(4-Chlorophenyl)Piperidin-1-Yl)Propyl)Pyrrolo[1,2-A]Quinoxalin-4(5H)-One

CAS: 1380392-05-1

5-(3-(4-(4-Chlorophenyl)Piperidin-1-Yl)Propyl)Pyrrolo[1,2-A]Quinoxalin-4(5H)-One

Purity: 97%

Molecular weight: 419.95g/mol

Ref: 54-OR1024227

JMS-17-2

CAS: 1380392-05-1

JMS-17-2

Purity: ≥98%

Molecular weight: 419.95g/mol

Ref: 54-BUP08794

JMS-17-2

CAS: 1380392-05-1

JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).

Formula: C₂₅H₂₆ClN₃O

Purity: 98.7% - 99.44%

Color and Shape: Solid

Molecular weight: 419.95

Ref: TM-T5849

5-(3-(4-(4-Chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one

CAS: 1380392-05-1

Purity: 97.0%

Molecular weight: 419.95001220703125

Ref: 10-F545292

JMS-17-2

CAS: 1380392-05-1

JMS-17-2 is a small molecule that was shown to have a potent and selective inhibitory effect on the production of chemokines in cancer cells. It blocks the interaction between CXCL12 and its receptor, CXCR4. This interaction is important for normal bone tissue development and function, as well as for chemotaxis and metastasis of cancer cells. JMS-17-2 has been shown to prevent tumor growth in animal models by inhibiting angiogenesis, or the formation of new blood vessels to supply nutrients to tumors. The drug also inhibits tumor growth by decreasing the number of primary tumors, reducing bone lesions, and inhibiting the progression of pancreatic cancer. Clinical trials are currently being conducted to assess the efficacy of JMS-17-2 in humans with advanced solid tumors.

Formula: C₂₅H₂₆ClN₃O

Purity: Min. 95%

Molecular weight: 419.95 g/mol

Ref: 3D-FFC39205