CAS 138112-76-2: Agomelatine

Description: Agomelatine is a synthetic compound primarily used as an antidepressant, classified as a melatonergic agent. It acts as an agonist at melatonin receptors (MT1 and MT2) and as an antagonist at serotonin receptors (5-HT2C), which contributes to its mood-regulating effects. The substance is known for its unique mechanism of action, promoting sleep regulation and circadian rhythm normalization, making it distinct from traditional antidepressants. Agomelatine is typically administered orally and is characterized by its relatively favorable side effect profile, with a lower incidence of sexual dysfunction and weight gain compared to other antidepressants. Its chemical structure includes a naphthalene ring, which is integral to its pharmacological activity. The compound is metabolized primarily in the liver, and its pharmacokinetics are influenced by factors such as age and liver function. Overall, Agomelatine represents a novel approach to treating major depressive disorder, particularly in patients with sleep disturbances.

Formula: C₁₅H₁₇NO₂

InChI: InChI=1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17)

InChI key: InChIKey=YJYPHIXNFHFHND-UHFFFAOYSA-N

SMILES: O=C(NCCC1=CC=CC2=CC=C(OC)C=C21)C

Synonyms:

• Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]-
• Aglomelatine
• Ago 178
• N-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide
• N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide
• N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide
• S 20098
• Thymanax
• Valdoxan
• Agomelatine

Agomelatine

CAS: 138112-76-2

• Formula: C₁₅H₁₇NO₂
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 243.31

Agomelatine

CAS: 138112-76-2

Agomelatine (Valdoxan), like melatonin, boosts mood by targeting melatonin and 5-HT2C receptors.

• Formula: C₁₅H₁₇NO₂
• Purity: 99.92%
• Color and Shape: White Solid
• Molecular weight: 243.3

Agomelatine

CAS: 138112-76-2

• Purity: 99.91%
• Molecular weight: 243.3g/mol

Agomelatine

CAS: 138112-76-2

• Formula: C₁₅H₁₇NO₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 243.31

Agomelatine

CAS: 138112-76-2

• Purity: 99%
• Molecular weight: 243.3g/mol

Agomelatine

CAS: 138112-76-2

• Formula: C₁₅H₁₇NO₂
• Molecular weight: 243.30

Agomelatine

CAS: 138112-76-2

• Formula: C₁₅H₁₇NO₂
• Color and Shape: Neat
• Molecular weight: 243.30

Agomelatine

CAS: 138112-76-2

• Formula: C₁₅H₁₇NO₂
• Color and Shape: Off-White
• Molecular weight: 243.30

N-(2-(7-Methoxynaphthalen-1-yl)ethyl)acetamide

CAS: 138112-76-2

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 243.30599975585938

Agomelatine - Bio-X ™

CAS: 138112-76-2

Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin receptors. It …

• Formula: C₁₅H₁₇NO₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 243.3 g/mol

Agomelatine

CAS: 138112-76-2

A competitive antagonist of 5-HT2B and 5-HT2C serotonin receptors. A melatonin analog and an agonist …

• Formula: C₁₅H₁₇NO₂
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 243.3 g/mol