CAS 138112-76-2
:Agomelatine
Description:
Agomelatine is a synthetic compound primarily used as an antidepressant, classified as a melatonergic agent. It acts as an agonist at melatonin receptors (MT1 and MT2) and as an antagonist at serotonin receptors (5-HT2C), which contributes to its mood-regulating effects. The substance is known for its unique mechanism of action, promoting sleep regulation and circadian rhythm normalization, making it distinct from traditional antidepressants. Agomelatine is typically administered orally and is characterized by its relatively favorable side effect profile, with a lower incidence of sexual dysfunction and weight gain compared to other antidepressants. Its chemical structure includes a naphthalene ring, which is integral to its pharmacological activity. The compound is metabolized primarily in the liver, and its pharmacokinetics are influenced by factors such as age and liver function. Overall, Agomelatine represents a novel approach to treating major depressive disorder, particularly in patients with sleep disturbances.
Formula:C15H17NO2
InChI:InChI=1/C11H14N4O2.CH4O3S/c1-5-2-9(16)7-3-8(14-15-11(12)13)10(17)4-6(5)7;1-5(2,3)4/h3-5,9,16H,2H2,1H3,(H4,12,13,15);1H3,(H,2,3,4)/b14-8-;
InChI key:InChIKey=YJYPHIXNFHFHND-UHFFFAOYSA-N
SMILES:C(CNC(C)=O)C=1C2=C(C=CC(OC)=C2)C=CC1
Synonyms:- Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]-
- Aglomelatine
- Ago 178
- N-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide
- N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide
- N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide
- S 20098
- Thymanax
- Valdoxan
- Agomelatine
- AGOMELATIN
- n-(2-(7-methoxynaphth-1-yl)ethyl)acetamide
- n-(2-(7-methoxy-1-naphthalenyl)ethyl)-acetamid
- S20098,N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide
- See more synonyms
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Found 11 products.
Agomelatine
CAS:Formula:C15H17NO2Purity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:243.31Agomelatine
CAS:<p>Agomelatine (Valdoxan), like melatonin, boosts mood by targeting melatonin and 5-HT2C receptors.</p>Formula:C15H17NO2Purity:99.92%Color and Shape:White SolidMolecular weight:243.3Agomelatine - Bio-X ™
CAS:Controlled Product<p>Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin receptors. It was designed to treat mood disorders, such as depression. It has been shown to improve mood by increasing the levels of certain neurotransmitters in the brain such as dopamine and noradrenaline. Agomelatine has beneficial phase-shifting effects in humans; it causes a sleep phase advance, a drop in body temperature, and an initial release of melatonin. According to controlled human studies, Agomelatine is equally effective at treating severe depression as the SSRI antidepressants paroxetine and sertraline.</p>Formula:C15H17NO2Purity:Min. 95%Color and Shape:PowderMolecular weight:243.3 g/molAgomelatine
CAS:Controlled Product<p>A competitive antagonist of 5-HT2B and 5-HT2C serotonin receptors. A melatonin analog and an agonist of melatonin receptors MT1 and MT2. Has potential as an anti-depressant agent.</p>Formula:C15H17NO2Purity:Min. 95%Color and Shape:White PowderMolecular weight:243.3 g/molN-(2-(7-Methoxynaphthalen-1-yl)ethyl)acetamide
CAS:Formula:C15H17NO2Purity:98%Color and Shape:SolidMolecular weight:243.306
