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CAS 138330-18-4

:

Incadronate

Description:
Incadronate, with the CAS number 138330-18-4, is a chemical compound that belongs to the class of bisphosphonates, which are primarily used in the treatment of bone-related disorders. It is characterized by its ability to inhibit osteoclast-mediated bone resorption, making it effective in conditions such as osteoporosis and Paget's disease. Incadronate exhibits a high affinity for hydroxyapatite, a mineral component of bone, which enhances its therapeutic efficacy. The compound is typically administered via injection and has a relatively long half-life, allowing for less frequent dosing compared to some other bisphosphonates. Its mechanism of action involves the disruption of the mevalonate pathway, leading to decreased osteoclast activity and increased bone density. Additionally, Incadronate has been studied for its potential effects on cancer-related bone loss, showcasing its versatility in managing various bone health issues. As with other bisphosphonates, potential side effects may include gastrointestinal disturbances and, in rare cases, osteonecrosis of the jaw.
Formula:C8H19NO6P2·2Na
InChI:InChI=1S/C8H19NO6P2.2Na/c10-16(11,12)8(17(13,14)15)9-7-5-3-1-2-4-6-7;;/h7-9H,1-6H2,(H2,10,11,12)(H2,13,14,15);;
InChI key:InChIKey=YWTDPNGRTUPBIK-UHFFFAOYSA-N
SMILES:C(NC1CCCCCC1)(P(=O)(O)O)P(=O)(O)O.[Na]
Synonyms:
  • ((Cycloheptylamino)Methylene)Bis-Phosphonicacidisodiumsalt
  • Bisphonal
  • Cimadronate
  • Disodium (2-Cycloheptylethane-1,1-Diyl)Bis[Hydrogen (Phosphonate)]
  • Disodium cycloheptylaminomethylene bisphosphonate
  • Disodiumcycloheptylaminomethylenediphosphonate
  • Incadronate disodium
  • Incadronatesodium
  • Phosphonic acid, P,P′-[(cycloheptylamino)methylene]bis-, sodium salt (1:2)
  • Phosphonic acid, [(cycloheptylamino)methylene]bis-, disodium salt
  • See more synonyms
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