CAS 1383376-93-9

Pf-05236216 hydrochloride

CAS: 1383376-93-9

Pf-05236216 hydrochloride is a potent and selective inhibitor of the transient receptor potential vanilloid type 1 (TRPV1) ion channel. Pf-05236216 hydrochloride has been shown to inhibit TRPV1 activation by capsaicin, resiniferatoxin, and heat in vitro and in vivo. Pf-05236216 hydrochloride also inhibits acid-sensing ion channels (ASICs) at concentrations below those required for TRPV1 inhibition. Pf-05236216 hydrochloride has been used as a research tool to study the function of TRPV1 and ASICs, as well as in studies of cell biology and peptides.

Formula: C₁₈H₁₆ClFN₄O

Purity: Min. 95%

Molecular weight: 358.8 g/mol

Ref: 3D-IFC37693

PF-05236216

CAS: 1383376-93-9

PF-05236216 is a potent, selective, brain-penetrant CK1δ/ε inhibitor that modulates circadian rhythms in mice, supporting sleep and metabolic research.

Formula: C₁₈H₁₅FN₄O

Purity: 100% - 100%

Color and Shape: Solid

Molecular weight: 322.34

Ref: TM-T70812