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CAS 138370-13-5

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dynemicin P

Description:
Dynemicin P is a naturally occurring anthracycline antibiotic that exhibits notable antitumor properties. It is derived from the bacterium Micromonospora sp. and is characterized by its complex polycyclic structure, which includes a chromophore that contributes to its biological activity. The compound is known for its ability to intercalate into DNA, disrupting the replication process and leading to cell death, making it a subject of interest in cancer research. Dynemicin P is also recognized for its unique mechanism of action, which involves the generation of reactive oxygen species that can induce oxidative stress in cancer cells. Additionally, it has been studied for its potential use in targeted therapies due to its selective cytotoxicity towards certain tumor types. However, like many anthracyclines, dynemicin P may also exhibit toxicity to normal cells, which poses challenges in therapeutic applications. Overall, its distinct chemical properties and biological activities make dynemicin P a significant compound in the field of medicinal chemistry and oncology.
Formula:C28H21NO9
InChI:InChI=1/C28H21NO9/c1-9-22(33)25(36)20-10-4-2-3-5-11(10)26-27(9,37)28(20,38)12-8-15(32)18-19(21(12)29-26)24(35)17-14(31)7-6-13(30)16(17)23(18)34/h2-9,20,25-26,29-32,36-38H,1H3
Synonyms:
  • Dynemicin P
  • 9,8,14-(1)Butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione, 8,9,14,15-tetrahydro-1,4,6,8,17,20-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*,18R*))-
  • 1,4,6,8,17,20-hexahydroxy-18-methyl-8,9,14,15-tetrahydro-8,14,9-(butane[1,1,4]triyl)anthra[1,2-b]benzo[f]azocine-5,16,19-trione
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