CAS 138452-21-8

Fexofenadine hydrochloride

Description:

Fexofenadine hydrochloride is a second-generation antihistamine primarily used to alleviate allergy symptoms such as hay fever and urticaria. It is a white to off-white crystalline powder that is practically insoluble in water but soluble in organic solvents like ethanol and methanol. The compound operates as a selective antagonist of peripheral H1 receptors, which helps reduce the effects of histamine, a substance in the body that causes allergic symptoms. Fexofenadine is known for its minimal sedative effects compared to first-generation antihistamines, making it a preferred choice for patients who require relief from allergies without significant drowsiness. The substance is typically administered orally and is available in various formulations, including tablets and suspension. Its pharmacokinetics indicate that it has a rapid onset of action, with peak plasma concentrations occurring within a few hours after ingestion. Additionally, fexofenadine is generally well-tolerated, with a low incidence of side effects, making it a widely used medication in allergy management.

Formula: C₃₂H₃₉NO₄·ClH

InChI: InChI=1S/C32H39NO4.ClH/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27;/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36);1H

InChI key: InChIKey=RRJFVPUCXDGFJB-UHFFFAOYSA-N

SMILES: C(O)(C1CCN(CCCC(O)C2=CC=C(C(C(O)=O)(C)C)C=C2)CC1)(C3=CC=CC=C3)C4=CC=CC=C4.Cl

Synonyms:

• 2-(4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl]phenyl)-2-methylpropanoic acid hydrochloride
• 2-[4-(1-Hydroxy-4-{4-[Hydroxy(Diphenyl)Methyl]Piperidin-1-Yl}Butyl)Phenyl]-2-Methylpropanoic Acid Hydrochloride (1:1)
• 2-[4-[1-Hydroxy-4-[4-(Hydroxy-Diphenyl-Methyl)-1-Piperidyl]-Butyl]Phenyl]-2-Methyl-Propanoic Acid Hydrochloride
• Alernex
• Allegra
• Alpha,Alpha-Dimethyl-4-[1-Hydroxy-4-[4-(Hydroxydiphenylmethyl)-1-Piperidinyl]Butyl]-Benzeneacetic Acid Hydrochloride
• Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride
• Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride (1:1)
• Carboxyterfenadine,Terfenadinecarboxylate
• Fastofen
• Feksine
• Fexadyne
• Fexodine
• Fexofen
• Fexofenadine HCl
• Fexofenadine-D10 Hcl
• Fexofendine Hcl
• Mdl 16455A
• Rapido
• Telfast
• Telfast BD
• Terfenidine Carboxylate Hydrochloride
• Vivafeks
• Α,Α-Dimethyl-4-[1-Hydroxy-4-[4-(Hydroxydiphenylmethyl)-1-Piperidinyl]Butyl]Benzeneacetic Acid

Fexofenadine hydrochloride

CAS: 138452-21-8

Fexofenadine Hydrochloride is a carboxylated metabolic derivative of terfenadine and long-lasting selective histamine H1 receptor antagonist, with

Formula: C₃₂H₄₀ClNO₄

Purity: >99.99%

Color and Shape: White Crystalline Powder

Molecular weight: 538.12

Ref: TM-T1470L

Fexofenadine hydrochloride

CAS: 138452-21-8

Fexofenadine hydrochloride

Purity: ≥98%

Molecular weight: 538.12g/mol

Ref: 54-BUP11437

Fexofenadine Hydrochloride

CAS: 138452-21-8, 153439-40-8, 83799-24-0

Formula: C₃₂H₃₉NO₄·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 538.13

Ref: 3B-F0698