Gurmarin is a peptide derived from the leaves of the plant Gymnema sylvestre, commonly known for its traditional use in herbal medicine, particularly in managing diabetes and reducing sugar cravings. It is characterized by its ability to inhibit the sweetness perception in taste receptors, which is attributed to its interaction with the sweet taste receptors on the tongue. Gurmarin is a small protein consisting of a specific sequence of amino acids, and its structure contributes to its biological activity. The substance has garnered interest in research for its potential applications in weight management and metabolic health. Additionally, gurmarin is being studied for its effects on glucose metabolism and its possible role in the treatment of obesity and diabetes. As a naturally occurring compound, it is generally considered safe when consumed in moderate amounts, although further studies are needed to fully understand its pharmacological properties and long-term effects.

gurmarin

138464-10-5: Gurmarin is a peptide derived from the leaves of the plant Gymnema sylvestre, commonly known for its traditional use in herbal medicine, particularly in managing diabetes and reducing sugar cravings. It is characterized by its ability to inhibit the sweetness perception in taste receptors, which is attributed to its interaction with the sweet taste receptors on the tongue. Gurmarin is a small protein consisting of a specific sequence of amino acids, and its structure contributes to its biological activity. The substance has garnered interest in research for its potential applications in weight management and metabolic health. Additionally, gurmarin is being studied for its effects on glucose metabolism and its possible role in the treatment of obesity and diabetes. As a naturally occurring compound, it is generally considered safe when consumed in moderate amounts, although further studies are needed to fully understand its pharmacological properties and long-term effects.

<p>Gurmarin is a polycyclic diterpene that can be found in the bark of the G. lucidum tree. It has been shown to bind to glutamate receptors, which are ion channels that allow ions such as calcium and sodium to pass through cell membranes. Gurmarin has been shown to activate these receptors in vitro, and knockout or over-expression of these receptors in cells can lead to changes in receptor activity. Gurmarin has also been shown to have specific binding affinity for a certain type of receptor cell, which are cells with cation channels that may be involved in taste perception. The receptor binding site on the gurmarin molecule is thought to correspond with the sweet taste sensation.</p>

CAS 138464-10-5

gurmarin

Gurmarin

Ref: 3D-GUR-3810-PI