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CAS 138517-61-0

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Trost Ligand

Description:
Trost Ligand, identified by its CAS number 138517-61-0, is a chiral phosphine ligand commonly used in asymmetric synthesis and catalysis. It is characterized by its ability to form stable complexes with transition metals, which enhances the selectivity and efficiency of various chemical reactions, particularly in the context of enantioselective transformations. The ligand typically features a bulky, sterically demanding structure that provides a unique environment for substrate interaction, promoting the formation of chiral products. Trost Ligand is particularly noted for its application in palladium-catalyzed reactions, such as cross-coupling and hydrogenation processes. Its effectiveness stems from the balance of sterics and electronics, allowing for precise control over reaction pathways. Additionally, the ligand's solubility in organic solvents makes it versatile for various reaction conditions. Overall, Trost Ligand is a valuable tool in synthetic organic chemistry, contributing to advancements in the development of chiral molecules for pharmaceuticals and other applications.
Formula:C44H40N2O2P2
InChI:InChI=1S/C44H40N2O2P2/c47-43(37-27-13-17-31-41(37)49(33-19-5-1-6-20-33)34-21-7-2-8-22-34)45-39-29-15-16-30-40(39)46-44(48)38-28-14-18-32-42(38)50(35-23-9-3-10-24-35)36-25-11-4-12-26-36/h1-14,17-28,31-32,39-40H,15-16,29-30H2,(H,45,47)(H,46,48)/t39-,40-/m1/s1
InChI key:InChIKey=AXMSEDAJMGFTLR-XRSDMRJBSA-N
SMILES:P(C1=C(C(N[C@H]2[C@H](NC(=O)C3=C(P(C4=CC=CC=C4)C5=CC=CC=C5)C=CC=C3)CCCC2)=O)C=CC=C1)(C6=CC=CC=C6)C7=CC=CC=C7
Synonyms:
  • (1R,2R)-(+)-1,2-Diaminocyclohexane-N,N'-bis(2'-diphenylphosphinobenzoyl)
  • (1R,2R)-1,2-Bis[[2-(diphenylphosphanyl)benzoyl]amino]cyclohexane
  • (1R,2R)-1,2-Bis[[2-(diphenylphosphino)benzoyl]amino]cyclohexane
  • (1R,2R)-N,N′-Bis[o-(diphenylphosphino)benzoyl]cyclohexane-1,2-diamine
  • (R)-Trost ligand
  • (R,R)-DACH-Phenyl Trost Ligand
  • (R,R)-Dppba
  • (R,R)-Trost ligand
  • Benzamide, N,N′-(1R,2R)-1,2-cyclohexanediylbis[2-(diphenylphosphino)-
  • Benzamide, N,N′-1,2-cyclohexanediylbis[2-(diphenylphosphino)-, (1R-trans)-
  • See more synonyms
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