CAS 138584-35-7

(3S,4S,5S,6R)-6-[5-[2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]phenyl]tetrazol-2-yl]-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid

Description:

The chemical substance with the name "(3S,4S,5S,6R)-6-[5-[2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]phenyl]tetrazol-2-yl]-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid" and CAS number "138584-35-7" is a complex organic compound characterized by its multi-functional groups and stereochemistry. It features a tetrahydropyran ring, which contributes to its cyclic structure, and multiple hydroxyl groups that enhance its solubility and reactivity. The presence of a tetrazole moiety indicates potential bioactivity, as tetrazoles are often found in pharmaceuticals. Additionally, the compound contains a butyl group and a chloro substituent, which may influence its lipophilicity and biological interactions. The specific stereochemistry, denoted by the (3S,4S,5S,6R) configuration, suggests that the compound may exhibit chirality, potentially leading to different biological activities for its enantiomers. Overall, this substance is likely to be of interest in medicinal chemistry and pharmacology due to its intricate structure and potential therapeutic applications.

Formula: C₂₈H₃₁ClN₆O₇

InChI: InChI=1S/C28H31ClN6O7/c1-2-3-8-20-30-25(29)19(14-36)34(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)26-31-33-35(32-26)27-23(39)21(37)22(38)24(42-27)28(40)41/h4-7,9-12,21-24,27,36-39H,2-3,8,13-14H2,1H3,(H,40,41)/t21-,22-,23+,24-,27+/m0/s1

InChI key: InChIKey=NGFMQMUIOUSHGR-RTCYWULBSA-N

SMILES: C(C1=CC=C(C2=C(C=CC=C2)C3=NN(N=N3)[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)C=C1)N5C(CCCC)=NC(Cl)=C5CO

Synonyms:

• 1-[5-[4′-[[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl][1,1′-biphenyl]-2-yl]-2H-tetrazol-2-yl]-1-deoxy-β-D-glucopyranuronic acid
• L 158783
• β-D-Glucopyranuronic acid, 1-[5-[4′-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl][1,1′-biphenyl]-2-yl]-2H-tetrazol-2-yl]-1-deoxy-
• Losartan N2 Glucuronide

Losartan 2-glucuronide

CAS: 138584-35-7

Ref: 7W-GC0251

Losartan N2-glucuronide

CAS: 138584-35-7

Formula: C₂₈H₃₁ClN₆O₇

Color and Shape: White To Off-White Solid

Molecular weight: 599.04

Ref: 4Z-L-115

Losartan N2-Glucuronide (90%)

Controlled Product

CAS: 138584-35-7

Applications A metabolite of Losartan (L470500).
References Stearns, R.A., et al.: Drug Metab. Dispos., 19, 1160 ( (1991), Chen, T.S., et al.: J. Antibiotics, 46, 131 (1993), Alonen, A., et al.: Bioorg. Chem., 36, 148 (2008),

Formula: C₂₈H₃₁ClN₆O₇

Purity: 90%

Color and Shape: Off-White

Molecular weight: 599.03

Ref: TR-L470495

Losartan N2-glucuronide

CAS: 138584-35-7

Losartan N2-glucuronide is a custom synthesis that has been modified by fluorination, methylation, and monosaccharide modification. It is synthesized with click chemistry to create an oligosaccharide. This product is synthesized from saccharides (carbohydrates) and polysaccharides. Losartan glucuronide is a complex carbohydrate that has been glycosylated and sugar modified for high purity.

Formula: C₂₈H₃₁ClN₆O₇

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Molecular weight: 599.03 g/mol

Ref: 3D-ML09886

Losartan N2-Glucuronide-d4

Controlled Product

CAS: 138584-35-7

Formula: C₂₈D₄H₂₇ClN₆O₇

Color and Shape: Neat

Molecular weight: 603.059

Ref: TR-L470497

Losartan N2-glucuronide

CAS: 138584-35-7

Formula: C₂₈H₃₁ClN₆O₇

Molecular weight: 599.04

Ref: ST-EA-CP-L25061