CAS 138605-00-2

β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester, hydrochloride (1:1)

Description:

The chemical substance known as β-Alanine, N,N-dimethyl-, with the specified stereochemistry and CAS number 138605-00-2, is a complex organic compound characterized by its intricate structure, which includes multiple chiral centers and functional groups such as esters and hydroxyls. This compound is a derivative of β-alanine, an amino acid that plays a role in various biological processes. The presence of the dimethyl group suggests enhanced lipophilicity, which may influence its solubility and biological activity. The ester functional group indicates potential reactivity, particularly in hydrolysis reactions, which could affect its stability and bioavailability. Additionally, the hydrochloride form implies that the compound is a salt, likely enhancing its solubility in aqueous environments. Overall, this compound's unique structural features may confer specific pharmacological properties, making it of interest in medicinal chemistry and biochemistry. However, detailed studies would be necessary to fully elucidate its biological activity and potential applications.

Formula: C₂₇H₄₃NO₈·ClH

InChI: InChI=1S/C27H43NO8.ClH/c1-10-24(5)15-18(31)27(33)25(6)17(30)11-13-23(3,4)21(25)20(35-19(32)12-14-28(8)9)22(34-16(2)29)26(27,7)36-24;/h10,17,20-22,30,33H,1,11-15H2,2-9H3;1H/t17-,20-,21-,22-,24-,25-,26+,27-;/m0./s1

InChI key: InChIKey=VIRRLEDAYYYTOD-YHEOSNBFSA-N

SMILES: O[C@@]12[C@]3(C)[C@@]([C@H](OC(CCN(C)C)=O)[C@H](OC(C)=O)[C@@]1(C)O[C@](C=C)(C)CC2=O)(C(C)(C)CC[C@@H]3O)[H].Cl

Synonyms:

• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-6-yl 4-methylpentanoate hydrochloride (1:1)
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-6-yl N,N-dimethyl-beta-alaninate hydrochloride (1:1)
• (3R-(3-Alpha,4A-Beta,5-Beta,6-Beta,6A-Alpha,10-Alpha,10A-Beta,10B-Alpha))-Id
• 1H-Naphtho[2,1-b]pyran, β-alanine deriv.
• 6-(3-Dimethylaminopropionyl)forskolin hydrochloride
• Adehl
• Adehl (TN)
• Beta-Alanine,N,N-Dimethyl-,5-(Acetyloxy)-3-Ethenyldodecahydro-10,10B-Dihydrox
• Colforsin dapropate hydrochloride
• Colforsindapropatehydrochloride
• N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-
• Nkh 477
• Y-3,4A,7,7,10A-Pentamethyl-1-Oxo-1H-Naphtho(2,1-B)Pyran-6-Ylester,Hydrochlor
• β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester, hydrochloride
• β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester, hydrochloride (1:1)

NKH477

CAS: 138605-00-2

Formula: C₂₇H₄₄ClNO₈

Purity: 98%

Molecular weight: 546.0932

Ref: IN-DA01E1RR

NKH477

CAS: 138605-00-2

NKH477

Purity: ≥98%

Molecular weight: 546.09g/mol

Ref: 54-BUP21855

NKH477

CAS: 138605-00-2

NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.

Formula: C₂₇H₄₄ClNO₈

Purity: 98% - 98%

Color and Shape: Solid

Molecular weight: 546.09

Ref: TM-T16332

NKH 477

Controlled Product

CAS: 138605-00-2

Formula: C₂₇H₄₃NO₈·ClH

Color and Shape: Neat

Molecular weight: 546.093

Ref: TR-N605000

NKH 477

CAS: 138605-00-2

NKH 477 is a drug that has been shown to increase the amount of calcium in the cytosol of cells. It has been found to be effective at low doses, which may be due to its ability to activate phospholipase C and stimulate the release of calcium from intracellular stores. NKH477 is an analogue of glucagon-like peptide 1 (GLP-1) and has been shown to have similar effects on cardiac muscle, but with less effect on pancreatic beta cells.
The effect of NKH 477 on cardiac muscle was studied in vitro using papillary muscle strips from guinea pig hearts. The drug was shown to cause relaxation of the muscles by stimulating ryanodine receptors, which are responsible for releasing calcium from intracellular stores. This drug may also have potential as a treatment for type 2 diabetes mellitus by activating GLP-1 receptors in the pancreas.

Formula: C₂₇H₄₄ClNO₈

Purity: Min. 95%

Molecular weight: 546.09 g/mol

Ref: 3D-BN178886