Factor D inhibitor 6, identified by its CAS number 1386455-51-1, is a chemical compound that functions as a selective inhibitor of Factor D, an enzyme involved in the alternative pathway of the complement system. This pathway plays a crucial role in immune responses and inflammation. The compound is characterized by its ability to modulate complement activation, making it of interest in therapeutic applications for diseases where the complement system is dysregulated, such as certain autoimmune disorders and age-related macular degeneration. Factor D inhibitor 6 is typically studied in the context of its pharmacological properties, including its potency, selectivity, and potential side effects. Its molecular structure and specific interactions with biological targets are essential for understanding its mechanism of action and efficacy. As research progresses, the compound may contribute to the development of novel treatments aimed at controlling complement-mediated pathologies. However, detailed information regarding its physical and chemical properties, such as solubility, stability, and toxicity, would require further investigation and specific experimental data.

Factor D inhibitor 6

1386455-51-1: Factor D inhibitor 6, identified by its CAS number 1386455-51-1, is a chemical compound that functions as a selective inhibitor of Factor D, an enzyme involved in the alternative pathway of the complement system. This pathway plays a crucial role in immune responses and inflammation. The compound is characterized by its ability to modulate complement activation, making it of interest in therapeutic applications for diseases where the complement system is dysregulated, such as certain autoimmune disorders and age-related macular degeneration. Factor D inhibitor 6 is typically studied in the context of its pharmacological properties, including its potency, selectivity, and potential side effects. Its molecular structure and specific interactions with biological targets are essential for understanding its mechanism of action and efficacy. As research progresses, the compound may contribute to the development of novel treatments aimed at controlling complement-mediated pathologies. However, detailed information regarding its physical and chemical properties, such as solubility, stability, and toxicity, would require further investigation and specific experimental data.

<p>Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.</p>

CAS 1386455-51-1

Factor D inhibitor 6

Factor D inhibitor 6

Ref: TM-T38803