CAS 138661-02-6

Pentetreotide

Description:

Pentetreotide, with the CAS number 138661-02-6, is a synthetic octreotide analogue that is primarily used in medical applications, particularly in the diagnosis and treatment of neuroendocrine tumors. It is a cyclic peptide that mimics somatostatin, a hormone that inhibits the release of several other hormones and regulates various physiological functions. Pentetreotide is characterized by its ability to bind selectively to somatostatin receptors, particularly subtype 2, which are often overexpressed in certain tumors. This property makes it valuable for both imaging and therapeutic purposes, as it can be labeled with radioactive isotopes for scintigraphy or used in targeted radiotherapy. The substance is typically administered via subcutaneous or intravenous routes and has a relatively long half-life, allowing for sustained action in the body. Its pharmacokinetics and biodistribution are influenced by factors such as receptor affinity and tissue permeability, making it an important tool in the management of specific malignancies.

Formula: C₆₃H₈₇N₁₃O₁₉S₂

InChI: InChI=1/C63H87N13O19S2/c1-37(78)48(34-77)70-62(94)50-36-97-96-35-49(71-58(90)45(25-39-13-5-3-6-14-39)66-51(80)29-75(31-53(83)84)23-21-74(30-52(81)82)22-24-76(32-54(85)86)33-55(87)88)61(93)68-46(26-40-15-7-4-8-16-40)59(91)69-47(27-41-28-65-43-18-10-9-17-42(41)43)60(92)67-44(19-11-12-20-64)57(89)73-56(38(2)79)63(95)72-50/h3-10,13-18,28,37-38,44-50,56,65,77-79H,11-12,19-27,29-36,64H2,1-2H3,(H,66,80)(H,67,92)(H,68,93)(H,69,91)(H,70,94)(H,71,90)(H,72,95)(H,73,89)(H,81,82)(H,83,84)(H,85,86)(H,87,88)/t37-,38-,44+,45-,46+,47-,48-,49+,50+,56+/m1/s1

Synonyms:

• Pentetreotide [INN:BAN]
• Dtpa-Sms
• N-(2-((2-(Bis(carboxymethyl)amino)ethyl)(carboxymethyl)amino)ethyl)-N-(carboxymethyl)glycyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (3-8)-disulfide
• SDZ 215-811s
• Unii-G083B71P98
• L-Cysteinamide, N-(2-((2-(bis(carboxymethyl)amino)ethyl)(carboxymethyl)amino)ethyl)-N-(carboxymethyl)glycyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (3-8)-disulfide, (R-,(R*,R*))-
• N-{2-[{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]ethyl}-N-(carboxymethyl)glycyl-N-[10-(4-aminobutyl)-16-benzyl-4-[(1,3-dihydroxybutan-2-yl)carbamoyl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]phenylalaninamide
• N-{2-[{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]ethyl}-N-(carboxymethyl)glycyl-N-[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-16-benzyl-4-{[(2R,3R)-1,3-dihydroxybutan-2-yl]carbamoyl}-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]-D-phenylalaninamide

Pentetreotide

CAS: 138661-02-6

Pentetreotide: Indium-labeled, for neuroendocrine tumor imaging; a somatostatin analog DTPA-Octreotide conjugate.

Formula: C₆₃H₈₇N₁₃O₁₉S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1394.58

Ref: TM-T16469

Pentetreotide

CAS: 138661-02-6

Formula: C₆₃H₈₇N₁₃O₁₉S₂

Molecular weight: 1394.58

Ref: 4Z-PP-351001