CAS 138661-03-7
:Furnidipine
Description:
Furnidipine is a pharmaceutical compound classified as a calcium channel blocker, primarily used in the treatment of hypertension and certain types of angina. It works by inhibiting the influx of calcium ions through L-type calcium channels in vascular smooth muscle and cardiac tissue, leading to vasodilation and reduced cardiac workload. This mechanism helps to lower blood pressure and improve blood flow. Furnidipine is characterized by its lipophilicity, which enhances its absorption and distribution in the body. The compound is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Its safety profile includes common side effects such as headache, dizziness, and peripheral edema, but it is generally well-tolerated. As with other calcium channel blockers, caution is advised in patients with certain cardiovascular conditions. Overall, Furnidipine represents a valuable option in the management of cardiovascular diseases, contributing to improved patient outcomes in hypertension therapy.
Formula:C21H24N2O7
InChI:InChI=1S/C21H24N2O7/c1-12-17(20(24)28-3)19(15-8-4-5-9-16(15)23(26)27)18(13(2)22-12)21(25)30-11-14-7-6-10-29-14/h4-5,8-9,14,19,22H,6-7,10-11H2,1-3H3
InChI key:InChIKey=GGVUNNUOJDGCBK-UHFFFAOYSA-N
SMILES:C(OCC1CCCO1)(=O)C=2C(C(C(OC)=O)=C(C)NC2C)C3=C(N(=O)=O)C=CC=C3
Synonyms:- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, methyl (tetrahydro-2-furanyl)methyl ester
- CRE 319
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, 3-methyl 5-[(tetrahydro-2-furanyl)methyl] ester
- Furnidipine
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
Furnidipine
CAS:<p>Furnidipine significantly reduced AoD and AF and had antiarrhythmic and cardioprotective effects at low doses in a rat model.</p>Formula:C21H24N2O7Purity:99.64%Color and Shape:SolidMolecular weight:416.42
