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CAS 138680-08-7

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(R)-Zopiclone

Description:
(R)-Zopiclone is a chiral compound primarily used as a sedative and hypnotic agent for the treatment of insomnia. It belongs to the class of cyclopyrrolones and is characterized by its ability to enhance the effects of gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased inhibitory neurotransmission in the central nervous system. This results in sedative, anxiolytic, and muscle relaxant properties. The (R)-enantiomer is specifically noted for its pharmacological activity, while the (S)-enantiomer is less active. Zopiclone is typically administered in oral form and is known for its relatively rapid onset of action and short half-life, making it effective for short-term management of sleep disorders. Common side effects may include drowsiness, dizziness, and potential dependence with prolonged use. Due to its sedative effects, caution is advised when operating machinery or driving after consumption. As with many medications, it is important to use Zopiclone under medical supervision to mitigate risks and ensure appropriate use.
Synonyms:
  • 1-Piperazinecarboxylic acid, 4-methyl-, (5R)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester (9CI)
  • 1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester, (R)-
  • 5H-Pyrrolo[3,4-b]pyrazine, 1-piperazinecarboxylic acid deriv
  • 4-methyl-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo(3,4-b)pyrazin-5-yl ester-1-Piperazinecarboxylic acid
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