CAS 138729-47-2

Eszopiclone

Description:

Eszopiclone is a non-benzodiazepine sedative-hypnotic medication primarily used for the treatment of insomnia. It belongs to the class of drugs known as cyclopyrrolones and is characterized by its ability to enhance the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that promotes sleep. The chemical formula of eszopiclone is C17H17ClN6O3S, and it features a thiazole ring, a chlorinated phenyl group, and a pyrrolone structure, contributing to its pharmacological properties. Eszopiclone is typically administered orally and is known for its relatively rapid onset of action, making it effective for both sleep initiation and maintenance. Common side effects may include dizziness, headache, and potential for dependence with prolonged use. It is important to use eszopiclone under medical supervision due to the risk of tolerance and withdrawal symptoms. As with any medication, individual responses can vary, and it is essential to consider potential interactions with other drugs and underlying health conditions.

Formula: C₁₇H₁₇ClN₆O₃

InChI: InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/t16-/m0/s1

InChI key: InChIKey=GBBSUAFBMRNDJC-INIZCTEOSA-N

SMILES: O(C(=O)N1CCN(C)CC1)[C@@H]2N(C(=O)C=3C2=NC=CN3)C4=CC=C(Cl)C=N4

Synonyms:

• (+)-Zopiclone
• (5S)- 6-(5-Chloropyridin-2-yl)-7-[(4-methylpiperazin-1-yl)carboxy] -5,6-dihydro--pyrrolo[3,4-b]pyrazin-5-one
• (5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
• (S)-Eszopiclone
• (S)-Zopiclone
• 1-Piperazinecarboxylic acid, 4-methyl-, (5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
• 1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester, (S)-
• 5H-Pyrrolo[3,4-b]pyrazine, 1-piperazinecarboxylic acid deriv.
• Esopiclone
• Estorra
• Eszopiclona
• Lunesta

(S)-Zopiclone (Eszopiclone)

CAS: 138729-47-2

Formula: C₁₇H₁₇ClN₆O₃

Color and Shape: White To Off-White Solid

Molecular weight: 388.81

Ref: 4Z-Z-067

Eszopiclone

Controlled Product

CAS: 138729-47-2

Formula: C₁₇H₁₇ClN₆O₃

Color and Shape: Neat

Molecular weight: 388.81

Ref: 86-MM3545.00

Eszopiclone

Controlled Product

CAS: 138729-47-2

Applications Eszopiclone is the active stereoizomer of Zopiclone and belongs to the class of drug known as cyclopyrrones. It is a nonbenzodiazepine hypnotic agent used as a treatment for insomnia.This is a controlled substance (depressant) in the US but not in Canada.
References Gottesmann, C., et al.: Eur. J. Neurosci., 10, 409 (1998), Yoshimoto, M., et al.: Eur. Neuropsychopharmacol., 9, 29 (1999),

Formula: C₁₇H₁₇ClN₆O₃

Color and Shape: Off White

Molecular weight: 388.81

Ref: TR-E889150

Eszopiclone

Controlled Product

CAS: 138729-47-2

Modulator of GABA(A) receptors

Formula: C₁₇H₁₇ClN₆O₃

Purity: Min. 95%

Color and Shape: White To Light (Or Pale) Yellow Solid

Molecular weight: 388.81 g/mol

Ref: 3D-FE156792

Eszopiclone CIV

Controlled Product

CAS: 138729-47-2

Lactams, nesoi

Formula: C₁₇H₁₇ClN₆O₃

Color and Shape: White Light Yellow Crystalline Powder

Molecular weight: 388.10507

Ref: 45-1255850