CAS 13875-63-3

Ethenoadenine

Description:

Ethenoadenine, with the CAS number 13875-63-3, is a purine derivative that is structurally related to adenine, a fundamental component of nucleic acids. This compound features an etheno group, which introduces a double bond into the adenine structure, altering its chemical properties and biological activity. Ethenoadenine is known for its role as a mutagenic agent, as it can incorporate into DNA and lead to mispairing during replication, potentially resulting in mutations. Its presence in biological systems can affect nucleic acid stability and function. The compound is typically studied in the context of DNA damage and repair mechanisms, as well as its implications in cancer research. Ethenoadenine is soluble in polar solvents, and its reactivity is influenced by the presence of functional groups in its structure. Overall, this compound serves as an important model for understanding the effects of modified nucleobases on genetic material.

Formula: C₇H₅N₅

InChI: InChI=1S/C7H5N5/c1-2-12-4-11-6-5(7(12)8-1)9-3-10-6/h1-4H,(H,9,10)

InChI key: InChIKey=OGVOXGPIHFKUGM-UHFFFAOYSA-N

SMILES: C=12C=3N(C=NC1N=CN2)C=CN3

Synonyms:

• 1,N(6)-Ethenoadenine
• 1,N⁶-Ethenoadenine
• 1,N⁶-Ethyleneadenine
• 1H-Imidazo(2,1-i)purine
• 3H-Imidazo[2,1-i]purine
• Ethenoadenine
• ε-Adenine
• 1,N6-Ethyleneadenine

3H-Imidazo[2,1-i]purine

CAS: 13875-63-3

Formula: C₇H₅N₅

Molecular weight: 159.1481

Ref: IN-DA0019H7

1,N6-Ethenoadenine

CAS: 13875-63-3

Formula: C₇H₅N₅

Molecular weight: 159.15

Ref: 7W-GK9969

N6-Ethenoadenine

CAS: 13875-63-3

N6-Ethenoadenine is a nucleoside that is generated during DNA repair. It is formed by the enzymatic activity of the enzyme N6-adenosyltransferase in the presence of ATP and S-adenosylmethionine. It has been shown to be a potent inducer of DNA damage and mutagenesis, as well as an inhibitor of polymerase chain reaction (PCR) and DNA replication. N6-Ethenoadenine is also an agonist for P2Y receptors, which are important in chemical biology. This nucleoside may serve as a potential biomarker for genotoxic events, such as chemotherapy treatments or exposure to ionizing radiation.

Formula: C₇H₅N₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 159.15 g/mol

Ref: 3D-FE08004

1,N6-Ethenoadenine

Controlled Product

CAS: 13875-63-3

Formula: C₇H₅N₅

Color and Shape: Neat

Molecular weight: 159.148

Ref: TR-E678005