CAS 138774-94-4

(R)-N-FMOC-2-Naphthylalanine

Description:

(R)-N-FMOC-2-Naphthylalanine is a derivative of the amino acid alanine, characterized by the presence of a 2-naphthyl group and a fluorenylmethyloxycarbonyl (FMOC) protecting group. This compound is typically used in peptide synthesis, particularly in the solid-phase synthesis of peptides, due to the FMOC group, which allows for selective protection of the amino group. The (R) configuration indicates that it is one of the enantiomers of naphthylalanine, which can influence its biological activity and interactions. The presence of the naphthyl group contributes to its hydrophobic character, potentially affecting solubility and interaction with other molecules. Additionally, the compound is often utilized in research and development within the fields of medicinal chemistry and biochemistry, where the study of peptide structure and function is crucial. Its CAS number, 138774-94-4, uniquely identifies this specific chemical substance in chemical databases, facilitating its identification and procurement for laboratory use.

Formula: C₂₈H₂₃NO₄

InChI: InChI=1/C28H23NO4/c30-27(31)26(16-18-13-14-19-7-1-2-8-20(19)15-18)29-28(32)33-17-25-23-11-5-3-9-21(23)22-10-4-6-12-24(22)25/h1-15,25-26H,16-17H2,(H,29,32)(H,30,31)/t26-/m1/s1

SMILES: c1ccc2cc(ccc2c1)C[C@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12

Synonyms:

• Fmoc-D-3-(2-Naphthyl)-alanine
• Fmoc-3-(2-Naphthyl)-D-alanine
• Fmoc-D-2-Nal-OH
• Fmoc-2-D-Nal-OH
• Fmoc-D-2Nal-OH

N-Fmoc-3-(2-naphthyl)-D-alanine, 95%

CAS: 138774-94-4

N-Fmoc-3-(2-naphthyl)-D-alanine is an Fmoc-protected alanine derivative and an intermediate used in the preparation of phosphoserine-containing tetrapeptides with hydrophobic N-terminal acyl groups as inhibitors of the BRCA1 protein. This Thermo Scientific Chemicals brand product was originally part

Formula: C₂₈H₂₃NO₄

Purity: 95%

Color and Shape: White to pale cream, Powder

Molecular weight: 437.50

Ref: 02-H51974

Fmoc-D-2-Nal-OH

CAS: 138774-94-4

Bachem ID: 4017071.

Formula: C₂₈H₂₃NO₄

Purity: 99.8%

Color and Shape: Whitish Powder

Molecular weight: 437.5

Ref: 01-4017071

2-Naphthalenepropanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (αR)-

CAS: 138774-94-4

Formula: C₂₈H₂₃NO₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 437.4865

Ref: IN-DA0019IN

Fmoc-D-2-Nal-OH

CAS: 138774-94-4

Formula: C₂₈H₂₃NO₄

Molecular weight: 437.49

Ref: 7W-GM9881

3-Naphth-2-yl-D-alanine, N-FMOC protected

CAS: 138774-94-4

3-Naphth-2-yl-D-alanine, N-FMOC protected

Purity: 98%

Molecular weight: 437.49g/mol

Ref: 54-OR14601

Fmoc-3-(2-naphthyl)-D-alanine

CAS: 138774-94-4

Fmoc-3-(2-naphthyl)-D-alanine is a fluorescent pressor agent that can be used in supramolecular chemistry. It has an anion form and a cation form, which are both present in the filtrate. The chemical will also form micelles when mixed with water. Fmoc-3-(2-naphthyl)-D-alanine is acetylated and can be used to study the nature of agarose. Fmoc-3-(2-naphthyl)-D-alanine can be used to measure the concentration of sorbitol in chromatography. This chemical has been shown to bind to DNA under microscopy, making it useful for fluorescence microscopy studies.

Formula: C₂₈H₂₃NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 437.49 g/mol

Ref: 3D-FF47422

Fmoc-3-(2-Naphthyl)-D-alanine

CAS: 138774-94-4

M03149 - Fmoc-3-(2-Naphthyl)-D-alanine

Formula: C₂₈H₂₃NO₄

Purity: 96%

Color and Shape: White powder

Molecular weight: 437.495

Ref: 10-M03149

Fmoc-3-(2-naphthyl)-D-alanine

Controlled Product

CAS: 138774-94-4

Applications Fmoc-3-(2-naphthyl)-D-alanine is an intermediate used in the preparation of phosphoserine-containing tetrapeptides with hydrophobic N-terminal acyl groups as inhibitors of the BRCA1 protein.
References Yuan, Z., et al.: Med. Chem. Lett., 2, 767 (2011); Liu, T., et al.: ACS. Comb. Sci., 13, 537 (2011);

Formula: C₂₈H₂₃NO₄

Color and Shape: Neat

Molecular weight: 437.49

Ref: TR-F625050